Results 31 to 40 of about 1,977,118 (297)

Histone Demethylases as Counterbalance to H3K27me3 Silencing in Plants

iScience, 2020
Summary: The universal importance of epigenetic regulation has become explicit over the last decade. There is now a detailed understanding of the molecular signatures and chromatin-modifying enzymes determining epigenetic regulation.
Pedro Crevillén
doaj   +1 more source

How to extract and analyze pollen from internal organs and exoskeletons of fossil insects?

STAR Protocols, 2021
Summary: This protocol explains how to extract pollen from fossil insects with subsequent descriptions of pollen treatment. We also describe how to document morphological and ultrastructural features with light-microscopy and electron microscopy.
Friðgeir Grímsson, Silvia Ulrich, Reinhard Zetter, Thomas Hörnschemeyer, Michael S. Engel, Sonja Wedmann   +5 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Recent transcriptomic studies to elucidate the plant adaptive response to spaceflight and to simulated space environments

iScience, 2022
Summary: Discovering the adaptation mechanisms of plants to the space environment is essential for supporting human space exploration. Transcriptomic analyses allow the identification of adaptation response pathways by detecting changes in gene ...
Aránzazu Manzano, Eugénie Carnero-Diaz, Raúl Herranz, F. Javier Medina   +3 more
doaj   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Protocol for chloroplast purification and import assay in Arabidopsis

STAR Protocols
Summary: Chloroplasts are fundamental plant organelles in green plants and algae. As an endosymbiosis-originated organelle, most chloroplast proteins are encoded by nuclear genes, translated in the cytosol, and imported into the chloroplast.
Huan Zhao, Xinyue Wang, Liangsheng Wang
doaj   +1 more source

Positioning the Root Elongation Zone Is Saltatory and Receives Input from the Shoot

iScience, 2020
Summary: In the root, meristem and elongation zone lengths remain stable, despite growth and division of cells. To gain insight into zone stability, we imaged individual Arabidopsis thaliana roots through a horizontal microscope and used image analysis ...
Tobias I. Baskin, Simon Preston, Ellen Zelinsky, Xiaoli Yang, Melissa Elmali, Dimitrios Bellos, Darren M. Wells, Malcolm J. Bennett   +7 more
doaj   +1 more source

DNA Topoisomerase 1α Promotes Transcriptional Silencing of Transposable Elements through DNA Methylation and Histone Lysine 9 Dimethylation in Arabidopsis [PDF]

, 2014
RNA-directed DNA methylation (RdDM) and histone H3K9 dimethylation (H3K9me2) are related transcriptional silencing mechanisms that target transposable elements (TEs) and repeats to maintain genome stability in plants.
Chen, Xuemei, Dinh, Thanh Theresa, Ecker, Joseph R., Gao, Lei, Le, Brandon, Li, Dongming, Li, Shaofang, Li, Shengben, Liu, Xigang, Manavella, Pablo Andrés, O'leary, Michael, Pontes, Olga, Schmitz, Robert J., Weigel, Detlef, Zhao, Yuanyuan   +14 more
core   +5 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Protocol for biomass and carbon storage estimation in tropical rainforests via remote sensing imagery

STAR Protocols
Summary: Here, we present a protocol for estimating biomass and carbon sequestration in tropical rainforests. We describe steps for combining remotely sensed data from Sentinel-2 imagery with data collected from standard field surveys.
Dung Trung Ngo, Hoi Dang Nguyen, Hieu Huu Viet Nguyen, Ngoc Thi Dang, Roman Gorbunov, Nhung Cam Pham   +5 more
doaj   +1 more source