Results 141 to 150 of about 7,909,977 (297)

Variation in cell cultures of periwinkle, Catharanthus roseus

open access: yes, 1982
The occurrence of secondary metabolites in plant cell cultures is not any longer a subject of mere curiosity, but a focal point of bio-technological activity.
Kutney, J. P.   +2 more
core  

Nanotechnology in plant tissue culture: a review

open access: yesHorticultural Plant Journal
Plant tissue culture represents an advanced biotechnological technique for propagating and conserving threatened plant species efficiently. This method enables the rapid production of genetically identical plants under controlled sterile laboratory ...
Sabreena Jan   +4 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Transformation 1 - Plant Tissue Culture

open access: yes, 2003
Overview and Objectives - Tissue Culture This lesson explains the technique of tissue culture as used in plant transformation. It discusses important issues, such as the use of selectable markers, genotype specificity, and tissue culture alternatives. At
Lee, Don, Hain, Patricia
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Development of tetraploids in tissue culture: modern techniques and biotechnological innovations

open access: yes
Polyploidy, characterized by chromosome multiplication, plays a pivotal role in plant evolution and agricultural innovation. This review explores advanced methodologies for tetraploid development in tissue culture, highlighting chemical inducers such as ...
Mohamed, Heba I.   +6 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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