Results 131 to 140 of about 7,909,977 (297)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Cryopreservation of the Norway spruce tissue culture line able to produce extracellular lignin

, 2018
A cryopreservation method was developed for a Norway spruce (Picea abies L. Karst.) cell line characterised by highly vacuolated cells and ability to produce natural-like extracellular lignin in a cell suspension culture.
Sveriges lantbruksuniversitet., Viljamaa, Sonja,   +1 more
core   +1 more source

Application of Data Modeling, Instrument Engineering and Nanomaterials in Selected Medid the Scientific Recinal Plant Tissue Culture. [PDF]

Plants (Basel), 2023
Ji B, Xuan L, Zhang Y, Mu W, Paek KY, Park SY, Wang J, Gao W.   +7 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Theories Behind Plant Tissue Culture

, 2019
Basics of Plant Tissue Culture When introducing a foreign gene into a target genome in plant tissue, you need to grow the transgenic cell to a complete plant. This is done by plant tissue culture, a biotechnique based on the concept that an organ, tissue,
Yen, Yang
core  

Sodium Toxicity: Should NaOH Be Substituted by KOH in Plant Tissue Culture? [PDF]

Front Plant Sci, 2022
Doungous O, Al-Khayri JM, Kouassi MK.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Targeting of Nuclear Encoded Proteins to Chloroplasts: a New Insight into the Mechanism

, 2000
2
Yong Jik Lee, 황인환, Yong Woo Kim, Kyeong Tae Pih   +3 more
core  

Plant tissue culture challenges in Ethiopia and alternative options for low-cost media. [PDF]

F1000Res, 2022
Amare K, Dugassa G.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source