Results 111 to 120 of about 7,909,977 (297)
Biotecnología Vegetal, 2019 The erect prickly pear (Opuntia stricta Haw) is an important alternative used to feed ruminants during prolonged periods of drought. The objective of this research was to evaluate the effect of different types and concentrations of cytokinins on the ...
Lindomar Maria de Souza +4 more
doaj
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Plant StressPlants adapt to environmental stresses through transcriptional reprogramming, often coordinated by chromatin-based regulatory mechanisms. In this study, we developed Pelargonium graveolens transgenic lines overexpressing the Hordeum vulgare HVA1 gene, a ...
Zafar Iqbal Warsi +10 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
, 1973 A presentation slide reflecting a list of Tissue Culture and Cells, and labeled Life Science Flight Research Approach, Tissue Culture and ...
core
Plant Tissue Culture and Secondary Metabolites Production. [PDF]
Plants (Basel), 2022 Danova K, Pistelli L.
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
A Simple but Effective Combination of pH Indicators for Plant Tissue Culture. [PDF]
Plants (Basel), 2023 Funnekotter B, Mancera RL, Bunn E.
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source