Results 101 to 110 of about 7,909,977 (297)

Agrobacterium pRi TL-DNA rolB and TR-DNA Opine Genes Transferred to the Spiny Amaranth (Amaranthus spinosus L.), A Nutraceutical Crop

Food Technology and Biotechnology, 2013
In vitro rhizogenesis occurred with a characteristic pattern typical of transformed roots following explant (internode/leaf) inoculation of Amaranthus spinosus L. with four different wild type Agrobacterium rhizogenes strains.
Ajantaa Pal, Swasti S. Swain, Arup K. Mukherjee, Pradeep K. Chand   +3 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Metabolic suffering in Actinidia deliciosa callus growing medium

, 1994
Calluses of Actinidia deliciosa wcre grown in successive 45-days subcu[tures in Gambors as medium (20g/l sucrosese). In order to evaluate the changes that take place during tbe growth of the callus, we measured , at different times (10, 35 and 45 ...
N. Negrini, C. Alisi, S. Cocucci, M. Cocucci, A. Abruzzese, L. Espen, A. R. Leva, G.A. Sacchi, S. Morgutti   +8 more
core   +2 more sources

Practical Guide to In Vitro Clonal Propagation of Nicotiana benthamiana Using Axillary Shoot Induction

Bio-Protocol
This protocol outlines a reliable method for the micropropagation of Nicotiana benthamiana using axillary shoot branching. Axillary shoot induction involves stimulating the outgrowth of dormant buds located at the leaf axils, allowing for the development
Pradeep Deo
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Plant Cell Tissue Organ Cult.

, 2001
Calli cultures derived from the leaves of Saussurea medusa were selected on the basis of colour into three callus, A, B and C, which suggested different levels of metabolite accumulation. An improved reversed phase high performance liquid chromatographic
Li, MY, Zhao, Q, Xing, JM, Zhao, DX, Lu, DP   +4 more
core  

Optimization of vegetative propagation and micropropagation protocols for the conservation and large-scale cultivation of Aquilegia fragrans Benth

Discover Conservation
The present study aimed to establish a robust propagation protocol for the endangered medicinal species Aquilegia fragrans through rhizome cuttings and in vitro micropropagation techniques.
Irshad Ahmad Bhat, Khushboo Guleria, Anamika Kumari, Sajida Banoo, Zahoor A. Kaloo, Mudasir Fayaz   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Variability in potato tissue culture

, 1989
Tissue culture systems in potato (Solanum tuberosum L.) that involve a callus phase, such as regeneration of plants from protoplasts or expiants, can be accompanied by phenotypic variability, or somaclonal variation.
Bright, S. W. J., Fish, N., Bright, S.W.J., Jones, M.G.K., Jones, M. G. K., Karp, A., Foulger, D.   +6 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source