Results 101 to 110 of about 745,431 (303)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow

Nature Communications
Excessive bone marrow adipocytes (BMAds) accumulation often occurs under diverse pathophysiological conditions associated with bone deterioration. Estrogen-related receptor α (ESRRA) is a key regulator responding to metabolic stress.
Tongling Huang, Zhaocheng Lu, Zihui Wang, Lixin Cheng, Lu Gao, Jun Gao, Ning Zhang, Chang-An Geng, Xiaoli Zhao, Huaiyu Wang, Chi-Wai Wong, Kelvin W. K. Yeung, Haobo Pan, William Weijia Lu, Min Guan   +14 more
doaj   +1 more source

Methods to Quantify Nickel in Soils and Plant Tissues

Revista Brasileira de Ciência do Solo, 2015
In comparison with other micronutrients, the levels of nickel (Ni) available in soils and plant tissues are very low, making quantification very difficult.
Bruna Wurr Rodak, Milton Ferreira de Moraes, João Augusto Lopes Pascoalino, Adilson de Oliveira Junior, Cesar de Castro, Volnei Pauletti   +5 more
doaj   +1 more source

Transferring an optimized TAP-toolbox for the isolation of protein complexes to a portfolio of rice tissues [PDF]

, 2016
Proteins are the cell's functional entities. Rather than operating independently, they interact with other proteins. Capturing in vivo protein complexes is therefore crucial to gain understanding of the function of a protein in a cellular context ...
Cannoot, Bernard, De Jaeger, Geert, De Winne, Nancy, Dedecker, Maarten, Dumoulin, Lies, Eeckhout, Dominique, Gevaert, Kris, Persiau, Geert, Van De Slijke, Eveline, Van Leene, Jelle, Vandenabeele, Steven, Vercruysse, Leen, Wojsznis, Nathalie   +12 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The use of in-situ deployments to examine the success of water quality mitigation measures on a watercress farm

, 2009
Watercress has long been believed to affect macroinvertebrate communities in chalk streams. Harvesting and washing watercress damages plant tissues and releases isothiocyanates which are potential toxicants to Gammarus pulex (L.).
Dixon, M.J., Shaw, P.J.
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Plant Tissue Culture

The American Biology Teacher, 1981
Tissue culture is the propagation of plants through "cloning," an asexual method. The process consists of growing a portion of the original plant in vitro (an artificial environ ment), promoting its multiplication, and then transferring it to potting medium in a greenhouse environment. Tissue culture is based on the concept of totipotency, which is the
openaire   +2 more sources

Comparative Study of B Vitamins in Multiple Tissues of Oilseed Crops and Leafty Vegetables Reveal Sesame as a Valuable Resource in Vitamin B₃, B₆ and B₁₂

Antioxidants
B vitamins are essential micronutrients for human health with prominent antioxidant properties, capable of scavenging reactive oxygen species (ROS) and maintaining redox homeostasis, protecting cells from oxidative damage.
Yijia Zhang, Ting Zhou, Zishu Luo, Desawi Hdru Teklu, Lei Wang, Rong Zhou, Wei Wang, Jun You, Huan Li, Linhai Wang   +9 more
doaj   +1 more source

Carbon Isotope Ratio Fractionation among Plant Tissues of Soybean

Plant Phenome Journal, 2018
Carbon isotope ratio (δC) has been used as a proxy for water use efficiency (WUE) in several crops. We compared δC of soybean [ (L.) Merr.] tissues sampled at bloom with δC of mature seed (MS).
Avjinder S. Kaler, Sumandeep K. Bazzer, Alvaro Sanz-Saez, Jeffery D. Ray, Felix B. Fritschi, Larry C. Purcell   +5 more
doaj   +1 more source