Results 131 to 140 of about 1,709,329 (311)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Plant and animal life safely recovered from Biosatellite II [PDF]
, 1967 Preliminary analysis of Biosatellite II space flight effects on variety of plant and animal species under ...
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The effects of the U.S. Plant Variety Protection Act on wheat genetic improvement: [PDF]
The U.S. Plant Variety Protection Act (PVPA) of 1970 was meant to strengthen intellectual property protection for plant breeders. A model of investment under partial excludability is developed, leading to the hypotheses that any increase in excludability
Alston, Julian M., Venner, Raymond J.
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
COMPETITIVE ANALYSIS OF U.S. FOOD PROCESSING PLANTS [PDF]
This paper presents a model-based approach for competitive analysis of manufacturing plants in the U. S. food processing industry. As part of this approach, plant competitiveness is measured using Operational Competitiveness Ratings Analysis (OCRA) -- a ...
Jayanthi, Shekhar +2 more
core +1 more source
Vigorous propagation material and organic breeding in the Netherlands [PDF]
, 2011 Organic cultivation depends on robust and healthy propagation material and the availability of suitable plant varieties. To be able to facilitate organic farmers and growers, Wageningen UR and the Louis Bolk Institute carry out a variety of research ...
Scholten, Olga
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source