Results 81 to 90 of about 48,948 (285)
Intracellular coordination of potyviral RNA functions in infection
Frontiers in Plant Science, 2014 Establishment of an infection cycle requires mechanisms to allocate the genomes of (+)-stranded RNA viruses in a balanced ratio to translation, replication, encapsidation, and movement, as well as mechanisms to prevent translocation of viral RNA (vRNA ...
Kristiina eMäkinen, Anders eHafren
doaj +1 more source
Family Level Phylogenies Reveal Relationships of Plant Viruses within the Order Bunyavirales
Viruses, 2020 Bunyavirales are negative-sense segmented RNA viruses infecting arthropods, protozoans, plants, and animals. This study examines the phylogenetic relationships of plant viruses within this order, many of which are recently classified species ...
Venura Herath +3 more
doaj +1 more source
Patellins 3 and 6, two members of the
Molecular Plant Pathology, 2014 SummaryMovement proteins (MPs) encoded by plant viruses interact with host proteins to facilitate or interfere with intra‐ and/or intercellular viral movement. Using yeast two‐hybrid and bimolecular fluorescence complementation assays, we herein presentin vivoevidence for the interaction betweenAlfalfa mosaic virus(AMV)MPand ArabidopsisPatellin 3 ...
Peiró Morell, Ana +5 more
openaire +3 more sources
FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
How a Virus Circumvents Energy Barriers to Form Symmetric Shells [PDF]
arXiv, 2020 Previous self-assembly experiments on a model icosahedral plant virus have shown that, under physiological conditions, capsid proteins initially bind to the genome through an en masse mechanism and form nucleoprotein complexes in a disordered state, which raises the questions as to how virions are assembled into a highly ordered structure in the host ...
arxiv
Single virus fingerprinting by widefield interferometric defocus-enhanced mid-infrared photothermal microscopy [PDF]
arXiv, 2022 Clinical identification and fundamental study of viruses rely on the detection of viral proteins or viral nucleic acids. Yet, amplification-based and antigen-based methods are not able to provide precise compositional information of individual virions due to small particle size and low-abundance chemical contents (e.g., ~ 5000 proteins in a vesicular ...
arxiv
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
Exploring the Diversity of Mechanisms Associated With Plant Tolerance to Virus Infection
Frontiers in Plant Science, 2018 Tolerance is defined as an interaction in which viruses accumulate to some degree without causing significant loss of vigor or fitness to their hosts. Tolerance can be described as a stable equilibrium between the virus and its host, an interaction in ...
Dinesh Babu Paudel, Hélène Sanfaçon
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective People with HIV (PWH) on antiretroviral therapy (ART) still experience neurocognitive dysfunction and accelerated brain volume loss. To assess whether the serotonergic and dopaminergic systems are affected, we used [11C]DASB positron emission tomography (PET) to assess presynaptic serotonergic function and [18F]FDOPA PET to measure ...
Chuen‐Yen Lau +12 more
wiley +1 more source
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2015 Vitaly Citovsky
openalex +2 more sources