Results 241 to 250 of about 137,452 (295)

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

open access: yesAdvanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang   +22 more
wiley   +1 more source

Endogenous nege-like viral elements in arthropod genomes reveal virus-host coevolution and ancient history of two plant virus families. [PDF]

open access: yesJ Virol
Lu G   +12 more
europepmc   +1 more source

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

open access: yesAdvanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong   +8 more
wiley   +1 more source

Virus Diseases in Plants

open access: yesTECNICA ITALIANA-Italian Journal of Engineering Science, 2020
openaire   +3 more sources

Ionic Liquid‐Reinforced Multifunctional Hydrogel for the Treatment of Enterocutaneous Fistula

open access: yesAdvanced Materials, EarlyView.
ECFGel is a multifunctional hydrogel engineered to treat infection‐associated ECFs. ECFGel demonstrates outstanding mechanical and biological properties, facilitating easy application, reliable occlusion, and sterilization, while promoting effective healing of infected fistula tracts.
Jinjoo Kim   +7 more
wiley   +1 more source

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