Results 171 to 180 of about 5,516,075 (411)

Heterogeneous virus classification using a functional deep learning model based on transmission electron microscopy images (Preprint) [PDF]

arXiv
Viruses are submicroscopic agents that can infect all kinds of lifeforms and use their hosts' living cells to replicate themselves. Despite having some of the simplest genetic structures among all living beings, viruses are highly adaptable, resilient, and given the right conditions, are capable of causing unforeseen complications in their hosts ...
arxiv  

Estimation of temporal covariances in pathogen dynamics using Bayesian multivariate autoregressive models [PDF]

arXiv, 2016
It is well recognised that animal and plant pathogens form complex ecological communities of interacting organisms within their hosts. Although community ecology approaches have been applied to determine pathogen interactions at the within-host scale, methodologies enabling robust inference of the epidemiological impact of pathogen interactions are ...
arxiv  

Non-canonical Translation in Plant RNA Viruses

Frontiers in Plant Science, 2017
Viral protein synthesis is completely dependent upon the host cell's translational machinery. Canonical translation of host mRNAs depends on structural elements such as the 5′ cap structure and/or the 3′ poly(A) tail of the mRNAs.
Lyuba A Ryabova, M. Aranda, Miras M, M. Miras, W. Allen Miller, V. Truniger   +5 more
semanticscholar   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Insights into the Complexity and Functionality of Plant Virus Protein Phosphorylation

Molecular Plant-Microbe Interactions
Phosphorylation, the most extensive and pleiotropic form of protein posttranslation modification, is central to cellular signal transduction. Throughout the extensive co-evolution of plant hosts and viruses, modifications to phosphorylation have served ...
Yuansheng Wu, Na Liu, Chengxu Zheng, Dongyuan Li, Shanshan Li, Jianguo Wu, Shanshan Zhao   +6 more
doaj   +1 more source

Circular Networks from Distorted Metrics [PDF]

arXiv, 2017
Trees have long been used as a graphical representation of species relationships. However complex evolutionary events, such as genetic reassortments or hybrid speciations which occur commonly in viruses, bacteria and plants, do not fit into this elementary framework. Alternatively, various network representations have been developed.
arxiv  

Rapid Extraction of Intact Crystalline Inclusions from the Cells of Plants infected with Tobacco Mosaic Virus [PDF]

, 1954
M. Rubio Huertos
openalex   +1 more source

Inability of the brown citrus aphid (Toxoptera citricida) to transmit citrus psorosis virus under controlled conditions [PDF]

, 2020
Might Toxoptera citricida (BrCA) be a citrus psorosis virus (CPsV) vector? We examined CPsV transmission by the BrCA throughout two experiments. In experiment 1, 4 CPsV-infected plants bearing BrCA colonies were introduced in separated cages with 12 ...
Bertalmio, Ana, Hernandez-Rodriguez, Lester, Maeso, Diego, Rivas, Fernando, Roque, Rodolfo, Rubio, Leticia   +5 more
core  

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source