Results 71 to 80 of about 127,017 (298)

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

Modelling Plantar Pressure in a Smart Wearable Insole System Using Piezoresistive Sensors

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi)
Biomechanical analysis plays a crucial role in evaluating movement patterns and pressure distribution. It enables early detection of abnormal gait and posture that may lead to long-term musculoskeletal problems.
Sekhah Ulyana, Husneni Mukhtar, Willy Anugrah Cahyadi, Nigel Bryan Tang   +3 more
doaj   +1 more source

A new plantar axis for longitudinal study of gait characteristics

, 2016
This investigation involved the testing of the suitability of a new plantar axis for the longitudinal study of older adult gait. The targeting involved fastening of small flat robber plugs on the foot sole to provide digital marking in plantar pressure ...
Albert K. Chong, Chong, Albert K.
core   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

A comparative analysis of functional outcome of local steroid and PRP in plantar fasciitis

Journal of Bone and Joint Diseases
Background: Plantar fasciitis is a common orthopedic issue that affects the quality of life. Various modalities of treatment have been tried for this condition, extending from conservative treatment to surgical treatment.
Pankaj Rathore, Sahil Garg, Shivam Bhati
doaj   +1 more source

Relationships between foot dimensions and plantar pressure distributed in older people

, 2020
The relationship between plantar pressure under the foot and the dimensions of the foot are essential for shoe manufacturers to design suitable footwear and evaluate foot problems, especially for older people.
Ali A. Al-Kharaz, Nibras S. Abbas, Hanan Al-Hadeethi, Al-Hadeethi, Hanan, Albert Chong, Chong, Albert, Abbas, Nibras S., Al-Kharaz, Ali A.   +7 more
core   +1 more source

Treatment for plantar fasciitis with biomechanical socks. Preliminary results of a randomized clinical trial

, 2023
Introducción: La fascitis plantar es uno de los principales motivos de las consultas podológicas. Hay multitud de tratamientos para esta patología, entre los que destacamos tratamiento ortopodológico, físico y farmacológico.
Martínez Nova, Alfonso, Cera Medrano, María de los Reyes, Munuera Martínez, Pedro Vicente   +2 more
core   +1 more source

Self‐Powered All‐in‐One Wearable Bioelectronics Driven by Pneumatic Energy Buffering of Daily Footsteps

Advanced Science, EarlyView.
A pneumatic energy‐buffering strategy transforms transient and intermittent footsteps into quasi‐continuous electrical energy for a self‐powered wearable biosensing platform. The footwear‐integrated air‐pumping harvester, combined with the rationally designed power‐management system, powers a wearable ankle PPG device with reduced motion artifacts ...
Ji‐Seok Kim, Tae Woog Kang, Hyunjoon Yoo, Jawon Ha, Yunuo Huang, Hee Han, Chi Won Ahn, Woon‐Hong Yeo, Il‐Kwon Oh   +8 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Investigation of Plantar Pressure Distribution in Overweight and Obese Individuals

, 2020
Objective:The increase in the incidence and prevalence of orthopaedic foot diseases may be related to changes in the plantar pressure distribution in overweight/obese individuals. Therefore, the purpose of the present study was to investigate the plantar
Yasemin SALKIN, Serkan TAŞ
core   +1 more source