Results 181 to 190 of about 7,091,994 (270)

Motor Cortex Hyperexcitability Is Coupled to Neuromuscular Dysfunction in Aged Mice

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
Aged mice exhibited impaired motor behavior and neuromuscular hypoexcitability, yet cortical output to muscle was enhanced, and motor cortex layer V pyramidal neurons were hyperexcitable, with altered synaptic inputs and excitability‐related transcriptional changes.
Jose A. Viteri   +11 more
wiley   +1 more source

Morphometric and Paleobiological Insights Into Pleistocene Sicilian Wolf Populations

open access: yesActa Zoologica, Volume 107, Issue 4, Page 409-431, October 2026.
ABSTRACT The Pleistocene wolves (Canis lupus) from Sicily represent one of the few known insular populations of this species from that time period. Despite their potential relevance for understanding carnivore adaptations in insular contexts, no dedicated study has previously investigated their morphology and evolutionary significance.
Domenico Tancredi   +3 more
wiley   +1 more source

Inhibition of leucine‐rich kinase 2 (LRRK2) promotes peripheral axon regeneration via phosphorylation‐network remodelling

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 20, Page 6199-6224, October 2026.
Background and Purpose In contrast to neurons in the central nervous system, neurons in the peripheral nervous system can regenerate axons after injury via activation of a pro‐regenerative transcriptional programme. Pathogenic mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, and several small ...
Eun‐Hae Jang   +11 more
wiley   +1 more source

Postcranial anatomy of the Miocene hippopotamoids of Toros‐Menalla, Chad

open access: yesJournal of Anatomy, Volume 249, Issue 4, Page 924-949, October 2026.
We establish a framework for the identification of postcranial remains in hippopotamoids by describing and comparing for the first time two late Miocene hippopotamoids from Toros‐Menalla, Chad (Hexaprotodon garyam, an early hippopotamid, and Libycosaurus bahri, the last African anthracothere) with the common hippopotamus.
Lorenzo Scribano   +4 more
wiley   +1 more source

Functional morphology of trabecular bone in the calcaneus of African apes

open access: yesJournal of Anatomy, Volume 249, Issue 4, Page 883-898, October 2026.
Pan exhibits significantly higher calcaneal tuberosity trabecular thickness (Tb.Th) and bone volume fraction (BV/TV) than Gorilla, potentially reflecting higher triceps surae forces for vertical climbing. Both taxa have significantly higher Tb.Th and BV/TV in the anterior calcaneus; the difference is exaggerated in Gorilla, potentially reflecting ...
Christine M. Harper, Biren A. Patel
wiley   +1 more source

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