Results 201 to 210 of about 7,091,994 (270)

TRPC3‐Driven Calcium Microdomains Instruct Peripheral Nerve Regeneration With Protective Implications for Central Neurons

Advanced Science, Volume 13, Issue 53, 24 September 2026.
How localized Ca2+ signals orchestrate neural repair remains unclear. Here, we show that TRPC3‐driven calcium microdomains direct nerve repair by coupling spatially confined Ca2+ signals to axon regeneration. This module operates in injured peripheral neurons and correlates with neuroprotection in Parkinson's disease, revealing a spatial logic for ...
Yu Lu, Jianbo Zhao, Zhenli Xie, Yuan Wang, Ruolin Wang, Bianbian Wang, Chuhan Shen, Yali Chen, Jingyu Yao, Ziyang Li, Huadong Xu, Zuying Chai, Zhuoyu Zhang, Changhe Wang, Rong Huang   +14 more
wiley   +1 more source

Short-term and long-term effects of anterior and posterior surgical approaches on plantar pressure distribution in patients with cervical spondylotic myelopathy. [PDF]

Eur J Med Res
Zhang X, Wu Z, Sheng J, Li X, Xu A, Liu J, Song H, Sun B, Xu C, Qi M, Liu Y.   +10 more
europepmc   +1 more source

Cooptimized Sensing and Sole Mechanics Enable Embodied‐Intelligence Design of User‐Specific Smart Footwear

Advanced Intelligent Systems, Volume 8, Issue 9, September 2026.
An embodied codesign framework for smart footwear is presented, jointly tuning lattice mechanics and sensing for personalized plantar pressure monitoring. By integrating pneumatic sensing within 3D‐printed lattice soles, the system achieves accurate real‐time centre‐of‐pressure tracking with reduced sensor count and energy demand, demonstrating how ...
Fengyu Zhong, Marco Pontin, Amy Zavatsky, Perla Maiolino   +3 more
wiley   +1 more source

Hierarchically and Temporally Distinct Ca2+ Signaling Across Thalamic Nuclei During Nociceptive Stimulation

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Fiber photometry revealed Ca2+ dynamics across multiple thalamic nuclei during nociceptive stimulation. Notably, all recorded thalamic nuclei were activated by nociceptive stimulation. Moreover, medial thalamic nuclei exhibited markedly stronger Ca2+ responses than lateral nuclei, suggesting a medial‐lateral difference in thalamic responses.
Yao‐Hua Liu, Tian‐Yu Zhao, Jin Cheng, Li‐Ming Liu, Sha‐Sha Tao, Yu‐Jing Chen, Jia‐Qi Zhu, Fen‐Sheng Huang, Zhi‐Ping Cai, Fei Li, Yun‐Qing Li   +10 more
wiley   +1 more source

Immediate effects of extracorporeal radial pressure wave therapy on dystonia, static plantar pressure distribution, and balance in patients with Parkinson's disease. [PDF]

Front Aging Neurosci
Xu Z, Huang X, Liu Q, Peng B, Zhou L, Dong X, Dai G, Zhu X, Weng Z, Lei D, Chen X.   +10 more
europepmc   +1 more source

Global Epidemiology of Diabetic Foot: A Systematic Review and Meta‐Analysis

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Introduction Diabetic foot (DF) disease, including ulcerations, amputations, and infections, represents a major cause of morbidity and mortality in individuals with diabetes mellitus (DM). Despite their substantial clinical, social, and economic burden, robust global epidemiological estimates remain limited due to fragmented evidence and ...
Massimo Carollo, Ylenia Ingrasciotta, Salvatore Crisafulli, Francesco Maccarrone, Daniela Pellegrino, Alberto Francescon, Edoardo Mannucci, Andrea Fontana, Gianluca Trifirò   +8 more
wiley   +1 more source

Ultrasonography Cannot Exclude Osteomyelitis in Diabetic Foot Ulcers: A Cross‐Sectional Diagnostic Accuracy Study Against Magnetic Resonance Imaging

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Ultrasound is a valuable first‐line imaging tool for diabetic foot soft‐tissue infection but cannot reliably exclude osteomyelitis. MRI remains the preferred modality for evaluating suspected bone involvement. ABSTRACT Background and Aims Diabetic foot ulcers (DFUs) can lead to amputation, especially when complicated by osteomyelitis (OM) or soft ...
Maryam Haghighi‐Morad, Hadi Vahedi, Arian Yousefi Fard, Behrooz Mohammadkhani Pordanjani, Seyyed Taher Seyyed Mahmoudi   +4 more
wiley   +1 more source

Relation Between Calcaneal Fat Pad Thickness and Plantar Foot Ulceration in Patients With Type 2 Diabetes Mellitus

Journal of Foot and Ankle Research, Volume 19, Issue 3, September 2026.
ABSTRACT Introduction Thinning of fat pads may elevate the risk of developing plantar foot ulcers potentially resulting in lower‐extremity amputations. Evaluating whether fat pad thickness is associated with plantar foot ulceration could aid in early risk detection. This study therefore aims to compare fat pad thickness between type 2 diabetes mellitus
Sem J. van den Nieuwenhof, Margot H. M. Heijmans, Jeroen J. van der Reijden, Chantal D. Bakker, Roel H. D. Vaes   +4 more
wiley   +1 more source

Comparison of short controlled ankle motion boots and barefoot walking on spatiotemporal gait parameters and plantar pressure distribution. [PDF]

PLoS One
Muğrabi S, Feyzioğlu Ö.
europepmc   +1 more source

Lateral Wedge Insoles With and Without Contoured Arch Support for People With Knee Osteoarthritis and Foot Pain: A Pilot, Feasibility Randomized Controlled Trial

Journal of Foot and Ankle Research, Volume 19, Issue 3, September 2026.
ABSTRACT Background Lateral wedge insoles (LWIs) are a non‐surgical adjunct treatment for knee osteoarthritis (OA) that has been shown to reduce the knee adduction moment—a biomechanical risk factor for knee OA disease progression. Though worn in one's shoes, little is known of the effects of LWIs use on the foot or ankle.
Michael A. Hunt, Natasha M. Krowchuk, Haocheng Zhang, Michael B. Ryan, Trevor B. Birmingham, Jesse M. Charlton   +5 more
wiley   +1 more source