Results 51 to 60 of about 17,492,705 (293)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Influence of planting designs on winter thermal comfort in an urban park
Journal of Environmental Engineering and Landscape Management, 2018 Various planting designs behave in different ways on microclimate and thermal comfort due to mainly distinct features of vegetation type and ratio. The papers simulated the microclimate behavior and thermal comfort of different planting design scenarios ...
Nima Karimi Afshar +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2017 Stormwater ponds are widely used in urban developments to control and clean stormwater and add aesthetic appeal to the landscape. This dual function of residential stormwater systems can create conditions at odds for the optimal performance of either ...
Shangchun Hu, Gail Hansen, P. Monaghan
semanticscholar +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A new design approach for Süleyman Demirel University Botanical Garden
Turkish Journal of Forestry, 2019 Botanical gardens were first established only for scientific reasons, however, later they have been started to be used for educational and recreation reasons.
Şirin DÖNMEZ +2 more
doaj +1 more source
Design of the MIDES plant [PDF]
, 2021 Abstract This chapter presents the full design of two microbial desalination cells (MDCs) at pilot-plant scale from the MIDES project. The final MDC pilot unit design was based on the knowledge gained through up scaling of the MDC from lab- to prepilot scale.
Juan Arévalo +5 more
openaire +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
International Journal of Secondary Metabolite, 2017 Spartium junceum L., the natural vegetation of Turkey flora, is one of the indicator plants of the Mediterranean climate. Especially in rural landscape, they offer aesthetic wives with floral beauties in dense stains.
Nebahat Yıldırım +2 more
doaj +1 more source
Zanco Journal of Pure and Applied Sciences, 2022 The study was carried out to determine the differences in vegetative and yield characteristics of sweet corn (Zea mays L.). at different plant density and planting depths using Nelder wheel design, this design is used to create a continuous ...
Ghadeer Rashid Mohammad +1 more
doaj +1 more source