Results 121 to 130 of about 571,669 (314)
El estudio se realizó en la Empresa Pecuaria Bacuranao, del municipio Habana del Este (provincia La Habana, Cuba), con el objetivo de establecer una estrategia para la prevención y el control de intoxicaciones naturales por plantas fotosensibilizantes en
J. M Aparicio, Odalys González
doaj
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Influence of oral environment on diet choices in goats: a focus on saliva protein composition [PDF]
There is ample evidence that ruminants are capable of making choices between different foods that provide a more balanced diet that would be obtained by eating at random.
Baptista, ES +3 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Adem Kumbe, Birhanu Hordofa Bekele, Anaf Betelu Onate, Beshir Hussien, Dereje Teshome, Siraj Kelil Yabello Pastoral and Dryland Agriculture Research Center, Oromia Agricultural Research Institute, Yabello, EthiopiaCorrespondence: Adem Kumbe, Email ...
Kumbe A +5 more
doaj
The Discharge Permit Program Under the Federal Water Pollution Control Act of 1972 - Improvement of Water Quality Through the Regulation of Discharges from Industrial Facilities [PDF]
There has been a significant growth of legislation designed to improve the quality of life in American by regulating the way industrial facilities interact with their environments.
Amouric, Henri +3 more
core +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source

