Results 101 to 110 of about 201,967 (310)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Phytochemical and Histochemical Screening of Toxic Plant Based on Knowledge of Tengger Tribe in Ngadiwono Village, Pasuruan

Journal of Experimental Life Science, 2017
Around hundreds of plant's species have been confirmed to produce toxic that could endanger the life of human or domestic animals. Some of those plants have potentials to be developed as medicine.
Anggraeni In Oktavia, Jati Batoro, Serafinah Indriyani   +2 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Plants toxic to animals

, 2013
Submitted by Seth Robbins (srobbins@illinois.edu) on 2013-01-09T21:14:54Z No. of bitstreams: 1 toxic.zip: 54288920 bytes, checksum: 2081a34d2f354064f979ed94d9a779c8 (MD5)Made available in DSpace on 2013-01-09T21:14:54Z (GMT). No.
Williams, Mitsuko, Veterinary Medicine Library   +1 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Thyroid parafollicular cell hyperplasia and carcinoma in a sheep with enzootic calcinosis due to Nierembergia rivularis poisoning [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2020
M. Machado, M. Preliasco, C.O. Schild, R.A. Costa, A. Balserini, F. Giannitti, F. Riet-Correa   +6 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Dutch survey pyrrolizidine alkaloids in animal forage

, 2009
Pyrrolizidine alkaloids (PAs) are secondary plant metabolites produced by a number of plants from the Asteraceae (Compositae), Boriginaceae and Fabaceae (Leguminosae) families.
Jong, J., de, de Jong, J., Oosterink, J.E., Beumer, B., Mulder, P.P.J.   +4 more
core  

Evaluation of Toxic Properties for User of Interior Design Plants

, 2018
Günümüzde ticari bir sektörün parçası olarak yer alan iç mekân bitkileri, yaşam alanlarında estetik ve işlevsel özellikler için yaygın bir şekilde kullanılmaktadır. Özellikle ev, ofis, alışveriş merkezleri vb.
Çelik, Betül Hümeyra, Müdük, Burcu, Görür, Ayşegül, Zencirkıran, Murat   +3 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source