Results 81 to 90 of about 571,669 (314)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Evaluation of toxic action of fluorides on agricultural plants
Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2007 The toxicity of potassium fluoride, sodium fluoride and ammonium fluoride for pea, maize, oat and onion was studied. It was found that the level of the toxic influence had grown with increase of fluoride concentration in the media of growth (from 5 to ...
V. N. Grishko
doaj +1 more source
Tropane alkaloids in food [PDF]
A large number of wild and cultured plants produce secondary metabolites that are toxic to humans and animals. Through accidental or intentional mixing of these plants with normal food and feed the consumers of these products will be exposed to the ...
Adamse, P., Egmond, H.P., van
core +1 more source
Endocidal Regulation of Secondary Metabolites in the Producing Organisms [PDF]
, 2016 Secondary metabolites are defined as organic compounds that are not directly involved in the normal growth, development, and reproduction of an organism.
Bullard, Steven H +4 more
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The Use of Isihlambezo in the Upper Tugela Region
South African Family Practice, 1991 No abstract available.
Gary Morris, B.E. Mdlalose
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Acute spontaneous and experimental poisoning by Solanum pseudoquina in cattle [PDF]
Pesquisa Veterinária Brasileira: The epidemiology, toxic potential, and clinical and pathological presentation of acute spontaneous and experimental poisoning by Solanum pseudoquina are described.
Elaine Melchioretto +4 more
doaj +1 more source
Brine Shrimp Toxicity Evaluation of Some Tanzanian Plants Used Traditionally for the Treatment of Fungal Infections. [PDF]
, 2006 Plants which are used by traditional healers in Tanzania have been evaluated to obtain preliminary data of their toxicity using the brine shrimps test. The results indicate that 9 out of 44 plant species whose extracts were tested exhibited high toxicity
Hamza, Omar J M +10 more
core +1 more source