Results 61 to 70 of about 2,178,903 (302)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Toxic plants as possible human teratogens
Circumstantial evidence points to lupine toxin in goat's milk as cause of human birth defects.
W Kilgore +3 more
doaj
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
During the past few months several talks presented on this session have dealt with toxic plants which are commonly grown in gardens. A number of enquiries have been received at the Department of Agriculture regarding these trees, particularly with ...
Royce, Robert Dunlop
core +2 more sources
Reducing Livestock Losses to Toxic Plants [PDF]
More than 100 species of toxic plants infest Texas rangelands. These plants affect ranch businesses directly by causing livestock death. They also have such indirect effects as lower conception rates and weaning weights, increased supplemental feeding ...
Machen, Rick, McGinty, Allan
core +1 more source
Urban historical areas and buildings are structures that provide important information, culture and tradition transfer from the past to the present. These places are both an effective tourism area and a part of urban life.
Necmettin Gür, Özgür Kahraman
doaj +1 more source
Lithium in the Environment and its Effects on Higher Plants
Lithium (Li) is present in low concentrations in all parts of the biosphere, including living organisms. It reaches the terrestrial environment primarily through natural processes to which parent substrate was subjected during pedogenesis, and due to ...
Kastori Rudolf +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

