Results 51 to 60 of about 156,903 (247)

Aluminum Toxicity and Tolerance in Plants [PDF]

Plant Physiology, 1995
Aluminum (Al) is the most abundant metal in the earth's crust, comprising about 7% of its mass. Since many plant species are sensitive to micromolar concentrations of Al, the potential for soils to be Al toxic is considerable. Fortunately, most of the Al is bound by ligands or occurs in other nonphytotoxic forms such as aluminosilicates and ...
Peter R. Ryan, Emmanuel Delhaize
openaire   +3 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Toxic ornamental plants in Venezuela

Bonplandia, 2017
The aim of this research was to contribute information on toxic ornamental plants in Venezuela. Information on taxonomy, common names, habit, origin, status, location, propagation and toxicology (part of the plant, effects) was compiled from articles ...
Carlos Varela Romero, Guillermo Vizcarrondo, Mahinda Martínez   +2 more
doaj  

Toxic Plants and Their Impact on Livestock Health and Economic Losses: A Comprehensive Review

Journal of Toxicology
Plants are important components in sustaining the life of humans and animals, balancing ecosystems, providing animal feed and edible food for human consumption, and serving as sources of traditional and modern medicine.
Tagesu Abdisa, Tegegn Dilbato Dinbiso
doaj   +1 more source

Review on the Toxicity and Safety of Medicinal Plants during Pregnancy

Proceedings
Introduction: Although herbs are widely used and considered safe, they can be toxic, especially during pregnancy [...]
Aniket Rajesing Girase, Javesh Kashinath Patil, Devshree Yashwantbhai Patel, Harsha Vasudev Chaudhari, Sachinkumar Madhukar Mahajan   +4 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Acute spontaneous and experimental poisoning by Solanum pseudoquina in cattle [PDF]

Pesquisa Veterinária Brasileira
: The epidemiology, toxic potential, and clinical and pathological presentation of acute spontaneous and experimental poisoning by Solanum pseudoquina are described.
Elaine Melchioretto, Daiane Ogliari, Tainara R. Tineli, Franciéli A. Molossi, Aldo Gava   +4 more
doaj   +1 more source

Food plant toxicants and safety [PDF]

Environmental Toxicology and Pharmacology, 1998
The ADI as a tool for risk management and regulation of food additives and pesticide residues is not readily applicable to inherent food plant toxicants: The margin between actual intake and potentially toxic levels is often small; application of the default uncertainty factors used to derive ADI values, particularly when extrapolating from animal data,
Jan H. Koeman, Luciano Vittozzi, Jørn Gry, Pieter-Jan Bouwmeister, Jan Alexander, Andrew G. Renwick, Harri Vainio, Sandra Ciere, Harry A. Kuiper, Derek H Shrimpton, John L. Herrman, Gerrit J.A. Speijers, Piet A. van den Brandt, Gerrit M. Alink, A.J.Alexander Essers, Eileen Mortby   +15 more
openaire   +5 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Evaluation of toxic action of fluorides on agricultural plants

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2007
The toxicity of potassium fluoride, sodium fluoride and ammonium fluoride for pea, maize, oat and onion was studied. It was found that the level of the toxic influence had grown with increase of fluoride concentration in the media of growth (from 5 to ...
V. N. Grishko
doaj   +1 more source