Results 141 to 150 of about 503,732 (331)

Assessment of coronary artery outward remodeling in consequence of excision of epicardial adipose tissue in Ossabaw swine [PDF]

, 2017
Background Coronary artery disease (CAD) results from the buildup of cholesterol, inflammatory factors, and proliferating smooth muscle cells within a vessel wall. This plaque impedes on the vessel lumen, decreasing the space through which blood can flow,
Coderre, Kelly
core   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

Advanced Science, EarlyView.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu, Jia Yan, Yuyan Zhang, Xiaozhi Ming, Siqi Chen, Zhichao Zou, Nianjie Feng, Jianbo Xiao   +7 more
wiley   +1 more source

Plaque regression and plaque stabilisation in cardiovascular diseases

Indian Journal of Endocrinology and Metabolism, 2013
Atherosclerosis is characterized by formation of plaques on the inner walls of arteries that threatens to become the leading cause of death worldwide via its sequelae of myocardial infarction and stroke.
Tarun Dave, J Ezhilan, Hardik Vasnawala, Vinod Somani   +3 more
doaj   +1 more source

MO‐hHHO: Multi‐Objective Hybrid Harris Hawks Optimization for Prediction of Coronary Artery Disease

Advanced Intelligent Systems, EarlyView.
This article proposes a novel Multi‐Objective hybrid Harris Hawks Optimization (MO‐hHHO) algorithm for simultaneous feature selection and hyperparameter tuning in heart disease classification. The approach leverages adaptive exploration‐exploitation strategies to enhance convergence efficiency.
Anu Ragavi Vijayaraj, Subbulakshmi Pasupathi   +1 more
wiley   +1 more source

Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis

Signal Transduction and Targeted Therapy
At advanced phases of atherosclerosis, the rupture and thrombogenesis of vulnerable plaques emerge as primary triggers for acute cardiovascular events and fatalities. Pathogenic infection such as periodontitis-associated Porphyromonas gingivalis (Pg) has
Xiaofei Huang, Mengru Xie, Yixuan Wang, Xiaofeng Lu, Feng Mei, Kaiwen Zhang, Xinlong Yang, Guangjin Chen, Ying Yin, Guangxia Feng, Wencheng Song, Nianguo Dong, Xuliang Deng, Songling Wang, Lili Chen   +14 more
doaj   +1 more source

In silico analyses of metagenomes from human atherosclerotic plaque samples

Microbiome, 2015
Through several observational and mechanistic studies, microbial infection is known to promote cardiovascular disease. Direct infection of the vessel wall, along with the cardiovascular risk factors, is hypothesized to play a key role in the ...
S. Mitra, Daniela I. Drautz-Moses, Morten Alhede, Myat T. Maw, Yang Liu, Rikky W. Purbojati, Z. H. Yap, Kavita K. Kushwaha, Alexandra G. Gheorghe, T. Bjarnsholt, G. Hansen, H. Sillesen, H. Hougen, P. Hansen, Liang Yang, T. Tolker-Nielsen, S. Schuster, M. Givskov   +17 more
semanticscholar   +1 more source

Integration of Cholesterol Oxidase‐Based Biosensors on a Smart Contact Lens for Wireless Cholesterol Monitoring from Tears

Advanced Intelligent Systems, EarlyView.
The combination of a parity‐time symmetry wireless technology with a cholesterol sensor integrated into a smart contact lens enables high‐sensitivity cholesterol sensing at low concentration. Cholesterol plays a critical role in physiological functions, but elevated levels increase the risk of cardiovascular disease.
Yang Cui, Lin Zhuo, Yuta Nishina, Saman Azhari, Takeo Miyake   +4 more
wiley   +1 more source

Up-regulated expression of NHE1 and Netrin-1 in atherosclerotic plaque of ApoE-/-mice [PDF]

Jichu yixue yu linchuang, 2020
Objective To investigate whether ApoE-/- mouse atherosclerotic plaque tissue and RAW 264.7 simultaneously express sodium hydrogen exchanger 1 (NHE1) and neurite guidance factor-1 (netrin-1), and their co-localization and interaction.
YANG Hui, MO Xian-gang, WANG Lan, ZHANG Shi-yue
doaj  

Metalloproteinases and Vulnerable Atherosclerotic Plaques [PDF]

Trends in Cardiovascular Medicine, 2007
Plaque rupture is the main cause of myocardial infarctions and strokes. Ruptured plaques have thin, highly inflamed, and collagen-poor fibrous caps that contain elevated levels of proteases, including metalloproteinases (MMPs), which might weaken plaque caps and promote rupture.
openaire   +3 more sources

Harnessing Physiological Shear Stress in a Perfusion Bioreactor for Enhanced Endothelialization of Small‐Diameter Vascular Grafts

Advanced NanoBiomed Research, EarlyView.
Traditional static culture provides limited physiological relevance for evaluation of vascular grafts. A perfusion bioreactor system can provide more accurate in vitro model for evaluation of vascular grafts, exposing endothelial cells on 3D structure to physiological or pathological shear stress.
Praveesuda L. Michael, Yuen Ting Lam, Timothy C. Mitchell, Miguel Santos, Alex H. P. Chan, Xinying Liu, Angus J. Grant, Matthew J. Moore, David F. Fletcher, Richard P. Tan, Steven G. Wise   +10 more
wiley   +1 more source