Results 121 to 130 of about 575,333 (346)

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding, Yingjie Zhang, Li Zhang, Xinou Zheng, Miaomiao Niu, Yunxiao Jia, Xuezhuang Li, Hua Chen, Chao Guo, Tao Jiang, Yuqiong Zhao   +10 more
wiley   +1 more source

How periodontal disease may contribute to cardiovascular disease [PDF]

, 2000
No abstract ...
Kinane, D.F., Lowe, G.D.O.
core   +1 more source

High shear stress induces atherosclerotic vulnerable plaque formation through angiogenesis

Regenerative Biomaterials, 2016
Rupture of atherosclerotic plaques causing thrombosis is the main cause of acute coronary syndrome and ischemic strokes. Inhibition of thrombosis is one of the important tasks developing biomedical materials such as intravascular stents and vascular ...
Yi Wang, J. Qiu, Shisui Luo, Xiang Xie, Yiming Zheng, Kang Zhang, Z. Ye, Wanqian Liu, H. Gregersen, Guixue Wang   +9 more
semanticscholar   +1 more source

A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats

Animal Models and Experimental Medicine, EarlyView.
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies, Vitaris Kodogo, Johannes Frederik Wentzel, Francis Edwin Smit   +3 more
wiley   +1 more source

Human serum albumin nanoparticles loaded with phthalocyanine dyes for potential use in photodynamic therapy of atherosclerotic plaques [PDF]

, 2019
Diseases caused by obstruction or rupture of vulnerable plaques in the arterial walls such as cardiovascular infarction or stroke are the leading cause of death in the world.
Aljarilla, Ana, Banerjee, Shubhadeep, Escosura, Andres de la, Holappa, Lari, Krol, Silke, Martinelli, Chiara, Mäkinen, Petri I., Sengupta, Jayeeta, Setaro, Francesca, Szebeni, Janos, Torres, Tomas, Trohopoulos, Panagiotis N., Urbanics, Rudolf, Wu, LinPing, Ylä-Herttuala, Seppo   +14 more
core   +1 more source

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source

What Is the Added Value of Carotid CEUS in the Characterization of Atherosclerotic Plaque?

Medicina
Background and Objectives: Unstable atherosclerotic plaque in the arteries is one of the main risk factors for cerebral ischemia. Duplex ultrasound is a frequently used diagnostic method, but it has some limitations for microvascularization and ...
Andrejs Lioznovs, Maija Radzina, Laura Saule, Peteris Einars Grinbergs, Aigars Lacis   +4 more
doaj   +1 more source

Extra virgin olive oil and cardiovascular diseases: benefits for human health [PDF]

, 2017
The cardioprotective properties of Mediterranean Diet were demonstrated for the first time from the Seven Country Study. In the last few decades, numerous epidemiological studies, as well as intervention trial, confirmed this observation, pointing out ...
Cammisotto, Vittoria, Carnevale, Roberto, Castellani, Valentina, D'Amico, Alessandra, Fianchini, Luca, Nocella, Cristina, Novo, Marta, Stefanini, Lucia, Violi, Francesco   +8 more
core   +1 more source

Multi‐omics data mining combined with experimental validation reveals ferroptosis‐ and autophagy‐associated hub genes as diagnostic candidates and immune modulators in atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
Using the GSE225650 dataset, we performed differential expression gene (DEG) screening, Weighted Gene Coexpression Network Analysis (WGCNA), and immune infiltration profiling on atherosclerosis (AS) samples, yielding 104 shared candidate genes. Subsequently, these 104 candidate genes were intersected with ferroptosis‑ and autophagy‑related gene sets ...
Xinou Zheng, Jinling Zheng, Xuezhuang Li, Hua Chen, Li Zhang, Yuqiong Zhao, Yahao Ling   +6 more
wiley   +1 more source

MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity [PDF]

, 2014
Background—Plasmacytoid dendritic cells (pDCs) bridge innate and adaptive immune responses and are important regulators of immuno-inflammatory diseases. However, their role in atherosclerosis remains elusive.
Ait-Oufella, Hafid, Baker, Lauren L., Cambrook, Helen, Finigan, Alison J., Grassia, Gianluca, Hansson, Göran K., Harrison, James E., Hugues, Stéphanie, Ludewig, Burkhard, Maffia, Pasquale, Mallat, Ziad, Masters, Leanne M., Murphy, Deirdre, Reith, Walter, Reizis, Boris, Sabir, Suleman, Sage, Andrew P.   +16 more
core   +2 more sources