Results 101 to 110 of about 575,333 (346)

Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

Nature Communications, 2016
Endothelial to mesenchymal transition (EndMT) plays a major role during development, and also contributes to several adult cardiovascular diseases. Importantly, mesenchymal cells including fibroblasts are prominent in atherosclerosis, with key functions ...
S. Evrard, L. Lecce, K. Michelis, A. Nomura-Kitabayashi, Gaurav Pandey, K. Purushothaman, Valentina d’Escamard, Jennifer R. Li, Lahouaria Hadri, K. Fujitani, P. Moreno, L. Bénard, P. Rimmelé, A. Cohain, B. Mecham, G. Randolph, E. Nabel, R. Hajjar, V. Fuster, M. Boehm, J. Kovacic   +20 more
semanticscholar   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Ultrasound methods of imaging atherosclerotic plaque in carotid arteries: examinations using contrast agents

Journal of Ultrasonography, 2020
The primary technique for detecting the presence and monitoring the development of carotid atherosclerotic plaque is ultrasound. The development of ultrasound techniques has made it possible to precisely visualise not only blood flow, but also vessel ...
Fedak Andrzej, Chrzan Robert, Chukwu Ositadima, Urbanik Andrzej   +3 more
doaj   +1 more source

The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells [PDF]

, 2017
open12siopenD'Elios, Mario Milco; Vallese, Francesca; Capitani, Nagaja; Benagiano, Marisa; Bernardini, Maria Lina; Rossi, Mirko; Rossi, Gianpaolo; Ferrari, Mauro; Baldari, Cosima Tatiana; Zanotti, Giuseppe; DE BERNARD, Marina; Codolo, GaiaD'Elios, Mario ...

core   +1 more source

Imaging of the ulcerated carotid atherosclerotic plaque: a review of the literature

Insights into Imaging, 2017
Carotid atherosclerotic disease constitutes a major modern health problem whose diagnosis primarily relies on imaging. Grading of stenosis has been long used as the main factor for risk stratification and guiding of management.
V. Rafailidis, I. Chryssogonidis, T. Tegos, K. Kouskouras, A. Charitanti-Kouridou   +4 more
semanticscholar   +1 more source

Endothelial GPR68 Is Essential for Arteriogenesis and Represents a Therapeutic Target in a Model of Peripheral Artery Disease

Advanced Science, EarlyView.
Endothelial GPR68 is identified as a critical regulator of collateral artery growth in peripheral artery disease. Genetic and pharmacological evidence demonstrates that GPR68 integrates hemodynamic cues to drive monocyte recruitment and inflammatory remodeling, thereby promoting collateral arteriogenesis and tissue perfusion after ischemia ...
Yiyan Song, Senyi Peng, Zhilei Huang, Miao Yu, Mingyue Wu, Yuexin Zhu, Zeyi Zhou, Yongshan Liu, Yalin Zhang, Yu Huang, Zhongxing Wang, Fu‐Li Xiang, Jie Xu   +12 more
wiley   +1 more source

Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation[S]

Journal of Lipid Research, 2013
Lysophosphatidic acid (LPA), a bioactive lysophospholipid, accumulates in the atherosclerotic plaque. It has the capacity to activate mast cells, which potentially exacerbates plaque progression.
Martine Bot, Saskia C.A. de Jager, Luke MacAleese, H. Maxime Lagraauw, Theo J.C. van Berkel, Paul H.A. Quax, Johan Kuiper, Ron M.A. Heeren, Erik A.L. Biessen, Ilze Bot   +9 more
doaj   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Advanced Detection and Therapeutic Monitoring of Atherosclerotic Plaque Using CD36-Targeted Lipid Core Probe

Pharmaceutics
Background: Atherosclerotic diseases, including coronary heart disease and cerebrovascular disease, are leading causes of morbidity and mortality worldwide. Atherosclerosis is a chronic vascular condition marked by the accumulation of lipid plaque within
Tingting Gao, Siqi Gao, Maolin Qiao, Chuanlong Lu, Heng Wang, Hongjiu Zhang, Lizheng Li, Shule Wang, Ruijing Zhang, Honglin Dong   +9 more
doaj   +1 more source

ATHEROSCLEROTIC PLAQUE OF RENAL VASA RECTA ON PATIENT WITH CALCIUM STONE

Jurnal Urologi Indonesia, 2013
Objective: We would like to identify whether atherosclerotic plaque inside renal vasa recta correlates with the formation of calcium stone. Material & Method: Samples are taken from kidney tissue removed by nephrectomy due to stone and non-stone disease.
Sawkar Vijay Pramod, Suwandi Sugandi, Aaron T. Sihombing, Makmuri Makmuri   +3 more
doaj   +1 more source