Results 91 to 100 of about 98,121 (309)

CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis

, 2017
Atherosclerosis is the underlying etiology of cardiovascular disease, the leading cause of death worldwide. Atherosclerosis is a heterogeneous disease in which only a small fraction of lesions lead to heart attack, stroke, or sudden cardiac death.
Gabrielle Fredman, Ze Zheng, George Kuriakose, Dorweiler, Bernhard, Alan R. Tall, Rymond, Christina C., Bernhard Dorweiler, Christina C. Rymond, Doran, Amanda C., Ira Tabas, Tabas, Ira, Tall, Alan R., Sluimer, Judith C.; id_orcid, Amanda C. Doran, Judith C. Sluimer, Zheng, Ze, Fredman, Gabrielle, Cai, Bishuang, Ozcan, Lale, Kuriakose, George, Lale Ozcan, Sluimer, Judith C., Bishuang Cai, Joanne Hsieh, Hsieh, Joanne   +24 more
core   +1 more source

TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays

Arthritis &Rheumatology, EarlyView.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu, Zhu Yan, Xueting Peng, Meixuan Li, Juan Wang, Yan Zhang, Xiaoqian Hu, Mingzhu Zhou, Kaixuan Ren, Dan Zhang, Xingyi Guo, Yumin Xia, Huanhuan Huo   +12 more
wiley   +1 more source

What Is the Added Value of Carotid CEUS in the Characterization of Atherosclerotic Plaque?

Medicina
Background and Objectives: Unstable atherosclerotic plaque in the arteries is one of the main risk factors for cerebral ischemia. Duplex ultrasound is a frequently used diagnostic method, but it has some limitations for microvascularization and ...
Andrejs Lioznovs, Maija Radzina, Laura Saule, Peteris Einars Grinbergs, Aigars Lacis   +4 more
doaj   +1 more source

Progress in atherosclerotic plaque imaging

World Journal of Radiology, 2012
Cardiovascular diseases are the primary cause of mortality in the industrialized world, and arterial obstruction, triggered by rupture-prone atherosclerotic plaques, lead to myocardial infarction and cerebral stroke. Vulnerable plaques do not necessarily occur with flow-limiting stenosis, thus conventional luminographic assessment of the pathology ...
Soloperto Giulia, Casciaro Sergio
openaire   +3 more sources

Atherosclerotic plaque vulnerability as an explanation for the increased risk of stroke in elderly undergoing carotid artery stenting

, 2011
Background and Purpose-Recent randomized trials showed an increased periprocedural risk for stroke with increasing age in patients undergoing carotid artery stenting.
de Borst, G.J., de Kleijn, D.P.V., Gert Jan de Borst, Michiel L. Bots, Reichmann, B.L., de Vries, J.P.P.M., Guus W. van Lammeren, Bots, M.L., Gerard Pasterkamp, Boudewijn L. Reichmann, Frans L. Moll, Dominique P.V. de Kleijn, Jean-Paul P.M. de Vries, Moll, F.L., Pasterkamp, G., van Lammeren, G.W.   +15 more
core   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Cellular and molecular components of the atherosclerotic process: Primary colture and characterization of human vascular smooth muscle cells from carotid artery

, 2009
Introduction The last years were characterized by several studies proceeding to understand SMC heterogeneity. Animal models of rat or rabbit IT after endothelial lesion are presently the most studied models for atherosclerotic plaque formation and ...
Gagliano, Teresa
core  

Radial capacity and hemodynamics evaluation in vitro and implantable feasibility validation in vivo of thinner bioresorbable polymer vascular stents

BMEMat, EarlyView.
A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen, Tao Li, Zhongyou Li, Jingyuan Zhou, Zhuo Zhang, Yan Xiong, Rifang Luo, Yu Chen, Yunbing Wang, Ping Fu   +9 more
wiley   +1 more source

Neovascularization in Atherosclerotic Plaques: Clinical Implications, Detection, and Prevention Strategies

Reviews in Cardiovascular Medicine
Following the global increase in atherosclerotic cardiovascular diseases, the demand for the effective identification of high-risk factors that lead to atherosclerotic plaque rupture and the search for new therapeutic targets has also increased ...
Long Zhang, Chancui Deng, Sha Wang, Bei Shi, Guanxue Xu   +4 more
doaj   +1 more source

Carotid plaque stress analysis by fluid structure interaction based on in-vivo MRI: Implications to plaque vulnerability assessment

, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 2010.Stroke is one of the leading causes of death in the world, resulting mostly from the sudden rupture of atherosclerotic plaques.
Gao, Hao
core