Results 171 to 180 of about 143,458 (285)

Molecular Mechanism of the IRF1/NFE2L1‐DT/ALKBH5/Cx43 Axis in Radiation‐Induced Injury in Vascular Endothelial Cells Through Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li, Jia‐Wen Yang, Yong‐Rui Jia, Jie Zhang, Qiao Gou   +4 more
wiley   +1 more source

Bidirectional interplay between periodontal disease and carotid artery disease: a comprehensive holistic review. [PDF]

Front Cell Infect Microbiol
Hofer AM, Picos A, Dădârlat-Pop A, Popa M.   +3 more
europepmc   +1 more source

Impact of Proton Pump Inhibitor Use on Outcomes Following Carotid Artery Stenting for Asymptomatic Carotid Stenosis: A Population‐Based Cohort Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Carotid artery stenting (CAS) is an effective treatment for carotid stenosis. Proton‐pump inhibitors (PPIs) are commonly prescribed in the general population. However, the impact of PPI use on outcomes following CAS remains unknown. This study investigated the impact of PPI use on CAS using a retrospective, matched‐cohort analysis from the ...
Chia‐En Wong, Pang‐Shuo Perng, Pei‐Wen Chen, Yu Chang, Chih‐Hao Tien, Jung‐Shun Lee, Liang‐Chao Wang, Chih‐Yuan Huang   +7 more
wiley   +1 more source

Amplification of Light‐Ultrasound Interaction in a Pi‐Shifted Fiber Bragg Grating for Enhanced Ultrasonic Sensitivity

Laser &Photonics Reviews, EarlyView.
By precisely engineering the geometry of a fiber‐based optical resonator, the interaction between confined light and external ultrasound waves is significantly amplified without sacrificing light confinement, boosting the ultrasound detection sensitivity beyond 0.5 mPa/√Hz.
Tai‐Anh La, Rami Shnaiderman, Vasilis Ntziachristos   +2 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Unraveling atherosclerosis through single-cell RNA sequencing: insights into cellular heterogeneity and disease mechanisms. [PDF]

Einstein (Sao Paulo)
Serrano CV, Ribeiro ML, Bichuette LD, Matuck BRS, Severino P, Gollob KJ, Lima JAC, Libby P.   +7 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Commentary: Exploring the association between immune-inflammation index and carotid plaque formation: a cross-sectional study in a large Chinese health screening population. [PDF]

Front Endocrinol (Lausanne)
Hu Z, Dong H, Huang X.
europepmc   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Wall Shear Stress Distribution in Intracranial Atherosclerotic Disease and Associations With Vessel and Plaque Morphology. [PDF]

CNS Neurosci Ther
Lan L, Li S, Liu H, H L Ip V, Abrigo J, Tian X, Liu Y, Liu Y, Li Z, Liang T, Fan FSY, Ma SH, Ma K, Y M Ip B, Soo YOY, Leung H, Mok VCT, Fang H, Song B, Xu Y, Fan Y, Leung TW, Leng X.   +22 more
europepmc   +1 more source