Results 251 to 260 of about 575,333 (346)

Caspase Recruitment Domain Family Member 8: A Favorable Target in the Pathogenesis of Atherosclerosis. [PDF]

Rev Cardiovasc Med
Tian D, Liu L, Zeng GG, He J, Liu H, Ma D, Yang Z, Ma X, Cao Y, Xu C.   +9 more
europepmc   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Atherosclerotic plaque-derived extracellular vesicles mediate smooth muscle cell phenotypic switching and promote vascular remodeling : EVs promote VSMC phenotypic switching. [PDF]

Cell Mol Life Sci
Wang J, Shi X, Wang D, Gao J, Huang K, Li J, Dong W, Li Y, Guo H, Wang Y, Huang Z, Liu Z, Huang L, Pan L, Liu X, Zhu W, Peng M, Xu G.   +17 more
europepmc   +1 more source

LJ-1888, a selective antagonist for the A3 adenosine receptor, ameliorates the development of atherosclerosis and hypercholesterolemia in apolipoprotein E knock-out mice [PDF]

, 2018
Jeong, Lak Shin, Jeong, Se-Jin, Kim, Gyudong, Oh, Goo Taeg, Park, Jong-Gil, Yu, Jinha   +5 more
core   +1 more source

Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment

The FEBS Journal, EarlyView.
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley   +1 more source

Integration of Conventional and Radiomic Features From Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography/Magnetic Resonance Imaging for Multimodal Prediction of Symptomatic Carotid Atherosclerotic Plaques. [PDF]

J Am Heart Assoc
Li Q, Fu F, Chen J, Zhang Y, Zheng H, Liang D, Liu X, Hu Z, Li B, Zhang N.   +9 more
europepmc   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Atherosclerotic Fibrous Plaques in Women Present ECM Remodeling Linked to TGF-β. [PDF]

Circ Res
Sakkers TR, Mili E, Winter H, Kapteijn D, Perry RN, Barbera N, Watts K, Dias IR, Meteva D, Wesseling M, Mol BM, de Borst GJ, de Kleijn DPV, van der Laan SW, Civelek M, White SJ, Maegdefessel L, Mayr M, Pasterkamp G, Mokry M, Benavente ED, den Ruijter HM.   +21 more
europepmc   +1 more source

The Effect of Chlorhexidine Mouthwash on Blood Pressure: A Systematic Review and Meta‐Analysis

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Aim This study evaluated the effect of rinsing with a chlorhexidine containing mouthwash (CHX‐MW) on blood pressure (BP), as compared to rinsing with a control MW or no MW, based on (randomised) controlled trials and observational studies in humans. PROSPERO CRD42020222495.
Lars S. J. Toonen, Bregje W. M. Van Swaaij, Melissa L. Vagevuur, Fridus (G. A.) Van der Weijden, Mark F. Timmerman, Dagmar Else Slot   +5 more
wiley   +1 more source

Research progress on macrophage regulation of atherosclerosis. [PDF]

Front Cardiovasc Med
Song J, Yan R, Li P, Guo J, Zhai G, Li J.   +5 more
europepmc   +1 more source