Results 91 to 100 of about 786,255 (313)

The galectin-3/RAGE dyad modulates vascular osteogenesis in atherosclerosis [PDF]

, 2013
Vascular calcification correlates with inflammation and plaque instability in a dual manner, depending on the spotty/granular (micro) or sheet-like/lamellated (macro) pattern of calcification.
BLASETTI FANTAUZZI, Claudia, Carlo M., Pesce, Familiari, Giuseppe, Iacobini, Carla, Menini, Stefano, Pugliese, Giuseppe, Relucenti, Michela, Ricci, Carlo, Salvi, Laura, Taurino, Maurizio   +9 more
core   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Combining Biomarkers and Imaging for Short‐Term Assessment of Cardiovascular Disease Risk in Apparently Healthy Adults

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Current strategies for cardiovascular disease (CVD) risk assessment focus on 10‐year or longer timeframes. Shorter‐term CVD risk is also clinically relevant, particularly for high‐risk occupations, but is under‐investigated.
Maria Odette Gore, Colby R. Ayers, Amit Khera, Christopher R. deFilippi, Thomas J. Wang, Stephen L. Seliger, Vijay Nambi, Elizabeth Selvin, Jarett D. Berry, W. Gregory Hundley, Matthew Budoff, Philip Greenland, Mark H. Drazner, Christie M. Ballantyne, Benjamin D. Levine, James A. de Lemos   +15 more
doaj   +1 more source

CT attenuation analysis of carotid intraplaque hemorrhage [PDF]

, 2018
Background and Purpose: Intraplaque hemorrhage is considered a leading parameter of carotid plaque vulnerability. Our purpose was to assess the CT characteristics of intraplaque hemorrhage with histopathologic correlation to identify features that allow ...
Bassareo, P. P., Cecco, C. N. D., Faa, X. G., Francone, M., Lai, L., Montisci, R., Saba, L., Sanfilippo, Rosa, Suri, J. S.   +8 more
core   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Comparative evaluation of herbal extract-containing mouthwash on periodontal parameters: A randomized controlled trial

SRM Journal of Research in Dental Sciences
Background: Plaque is the main causative agent in the onset and progression of periodontal diseases and is directly linked to the development of gingivitis.
Harsh D. Borundia, Surekha Rathod, Savita Sharma, Shivani Koli   +3 more
doaj   +1 more source

Flexible Dielectric Acoustic Resonator Patch for Tissue Regeneration

Advanced Materials, EarlyView.
A flexible dielectric acoustic resonator patch enables MHz‐range ultrasound generation through resonance amplification without using piezoelectric materials. Conformal integration on a curved substrate allows efficient acoustic delivery to tissue‐mimicking environments.
Donyoung Kang, Byeongseok Ryu, Sujeong Ahn, Junhyub Kim, Myeonghun Jang, Jeong Ho Cho, Won‐Gun Koh, Hyungsuk Lee   +7 more
wiley   +1 more source

Periodontal Diseases in Children and Adolescents

Česká Stomatologie a Praktické Zubní Lékařství, 2008
Periodontal diseases are the most common chronic conditions affecting the human race. Recently, increased attention has been given to these diseases because they were found to be related not only to oral health but also to many systemic diseases such as ...
K. Musilová, M. Kukletová, L. Izakovičová Hollá   +2 more
doaj  

Aβ Plaques.

Free neuropathology, 2020
Aβ plaques are one of the two lesions in the brain that define the neuropathological diagnosis of Alzheimer's disease. Plaques are highly diverse structures; many of them include massed, fibrillar polymers of the Aβ protein referred to as Aβ-amyloid, but some lack the defining features of amyloid.
openaire   +2 more sources