Results 101 to 110 of about 485,848 (308)

Matrix Metalloproteinase 9 as a Predictor of Coronary Atherosclerotic Plaque Instability in Stable Coronary Heart Disease Patients with Elevated Lipoprotein(a) Levels

Biomolecules, 2019
We sought to investigate whether levels of matrix metalloproteinases (MMPs) and their inhibitors predict coronary atherosclerotic plaque instability, as assessed by intravascular ultrasound (IVUS) virtual histology during coronary angiography.
Marat Ezhov, Maya Safarova, Olga Afanasieva, Maksim Mitroshkin, Yuri Matchin, Sergei Pokrovsky   +5 more
doaj   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Effect of commonly consumed sugar containing and sugar free fruit drinks on the hydrogen ion modulation of human dental plaque

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2014
Background: With the increased awareness of healthy diet among the population, the intake of fruit juices as health drinks has been increased. This study has been designed to check the potential cariogenicity of fruit drinks frequently consumed by ...
Nanika Mahajan, Bhanu Kotwal, Vinod Sachdev, Nivedita Rewal, Rakesh Gupta, Shefally Goyal   +5 more
doaj   +1 more source

Investigation into the formation and susceptibility of Candida albicans biofilms and denture plaque in vitro. [PDF]

, 2005
Microbial biofilms are wide-spread in nature and the organisms within them are often able to cause acute and chronic human diseases. The nature of biofilms is complex and the organisms behave differently from their planktonic counterparts.
Lamfon, H.
core  

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Imaging the Vulnerable Plaque

Journal of the American College of Cardiology, 2011
Cardiovascular diseases are still the primary causes of mortality in the United States and in Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and precipitates an acute vascular event, which is responsible for the high mortality rate.
Vancraeynest, D, Pasquet, A, Roelants, V, Gerber, Bernhard L, Vanoverschelde, Jean-Louis J   +4 more
openaire   +3 more sources

Potential of Magnetic Resonance Plaque Imaging Using Superparamagnetic Particles of Iron Oxide for the Detection of Carotid Plaque [PDF]

, 2008
Macrophages and by-products are important in plaque destabilization in atherosclerosis. Ultra-small superparamagnetic particles of iron oxide (SPIO)-enhanced magnetic resonance (MR) imaging may be suitable for the detection of macrophages in ...
Nagata, Izumi, Nakamoto, Morito, Tsutsumi, Keisuke, Morikawa, Minoru, Kawahara, Ichiro, Kitagawa, Naoki, Hayashi, Tomayoshi   +6 more
core   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Visualization of Vulnerable Coronary Plaque and Prevention of Plaque Rupture

Juntendo Medical Journal
In daily clinical practice, assessing anatomical findings and the presence or absence of ischemia is pivotal for determining the need for percutaneous coronary intervention. However, concurrently, comprehending vulnerability can greatly assist in predicting future cardiovascular events and formulating preventive strategies for individual patients. This
FUKASE, TATSUYA, DOHI, TOMOTAKA
openaire   +2 more sources

Plaque from Texas Tech University

, 2007
Plaque includes listing of victims from the College of Liberal Arts and Human ...
Texas Tech University
core