Results 131 to 140 of about 463,679 (318)

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

open access: yesAdvanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang   +9 more
wiley   +1 more source

Jack D. Farris Tree Plaque

open access: yes, 1984
This image was taken by Rebecca Vandewalle '12.Plaque inscription: "Jack D. Farris (1921 - 1998), T.K.
Vandewalle, Rebecca
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Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin   +11 more
wiley   +1 more source

Hunt Gateway Plaque

open access: yes, 1977
This image was taken by Rebecca Vandewalle '10.Plaque inscription:" The Hunt Gateway, erected in memory of William Ireys Hunt '34 (1913 - 1944), Captain Medical Corps Army of the United States."This plaque is located on the pillar at the ...

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Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

open access: yesAdvanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang   +10 more
wiley   +1 more source

Investigation into the formation and susceptibility of Candida albicans biofilms and denture plaque in vitro.

open access: yes, 2005
Microbial biofilms are wide-spread in nature and the organisms within them are often able to cause acute and chronic human diseases. The nature of biofilms is complex and the organisms behave differently from their planktonic counterparts.
Lamfon, H.
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A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

open access: yesAdvanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun   +11 more
wiley   +1 more source

Garner Court Plaque

open access: yes, 1998
This image was taken by Rebecca Vandewalle '12, a Rhodes College student, as part of a GIS class project..Plaque inscription:"Garner Court, dedicated in loving tribute to Tony Lee Garner (1942 - 1998)."This plaque is attached to the fountain on the west ...
Vandewalle, Rebecca
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Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

open access: yesAdvanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang   +10 more
wiley   +1 more source

Joe D. Jolly, III Plaque

open access: yes, 2010
Plaque inscription: "In honor of Joe D. Jolly, III 1958-1993 Whose great spirit continues to inspire" Class of 1981This plaque is located in the ground near the delivery entrance on the northwest side of the Paul Barret, Jr ...

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