Results 141 to 150 of about 463,679 (318)

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

open access: yesAdvanced Science, EarlyView.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian   +9 more
wiley   +1 more source

Administrative Staff Plaque

open access: yes, 2004
This document was received from the Communications Office in 2013. Uploaded by Archives RSA Emily Jordan, class of 2015, in 2013.This Plaque lists the names of the Administrators, Administrative Staff, and Administrative Services, from 1984 to 2004.This ...

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A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

open access: yesAdvanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng   +17 more
wiley   +1 more source

Faculty Awards Plaque

open access: yes, 2004
This document was received from the Communications Office in 2013. Uploaded by Archives RSA Emily Jordan, class of 2015, in 2014.This plaque lists the recipients of the Clarence Day Award for Outstanding Teaching and the Dean's Award for Research and ...

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Machine Learning‐Enhanced Ultrasensitive Immuno‐CRISPR Array Facilitates Early Diagnosis of Alzheimer's Disease by Detecting Multiple Plasma Biomarkers

open access: yesAdvanced Science, EarlyView.
This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Liding Zhang   +9 more
wiley   +1 more source

Douglas Brooks Room plaque

open access: yes, 1950
Image scanned and uploaded by Taylor Jackson, class of 2015.Plaque inscription reads: Dedicated in honor of Douglas W. Brooks. Businessman, public-spirited citizen and long-time friends of A.K. Burrow." It is located in the Burrow Refectory.This plaque

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Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

open access: yesAdvanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu   +8 more
wiley   +1 more source

Secondary Plaque Over Primary Plaque on Scalp

open access: yesIndian Dermatology Online Journal, 2021
Pangti, Rashi, Ahuja, Rhea, Bhari, Neetu
openaire   +2 more sources

Sigma Nu Brothers Plaque, 2005

open access: yes, 2005
This image was taken by Rebecca Vandewalle '12.Plaque inscription: "In honor of Epsilon Sigma brothers, Sigma Nu fraternity, dedicated October 7, 2005."This plaque is located in the green area north of Barret ...

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p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

open access: yesAdvanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu   +6 more
wiley   +1 more source

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