Results 221 to 230 of about 1,105,082 (410)

On the Plaque Expansivity Conjecture [PDF]

, 2015
It is one of the main properties of uniformly hyperbolic dynamics that points of two distinct trajectories cannot be uniformly close one to another. This characteristics of hyperbolic dynamics is called expansivity.
Kryzhevich, Sergey
core  

Mechanotransduction Activates Microglia and Impairs Phagocytosis in Stiff Amyloid‐β Plaques

Advanced Science, EarlyView.
The study constructs an in vitro Aβ plaque‐associated microglia model and uses SECM and SICM to in situ monitor changes in ROS levels, membrane permeability, and phagocytosis of microglia during Aβ clearance. It is found out that Aβ stiffness triggers microglial activation via the PIEZO1 mechanotransduction pathway, causing neuroinflammation and ...
Yulin Liu, Junjie Zhang, Yuxiang Zhao, Feixiang Fang, Siyu Zhang, Qiqi An, Jian Zhuang, Feng Xu, Fei Li   +8 more
wiley   +1 more source

Case of Parapsoriasis en Plaques [PDF]

, 1914
A. M. H. Gray
openalex   +1 more source

Ferrocene‐Functionalized Black Phosphorus Nanoplatform Enables Targeted and Prolonged MRI Visualization of Atherosclerotic Plaques

Advanced Science, EarlyView.
Aminoferrocene is employed to modify black phosphorus, generating stable phosphorus radicals (FcP). The FcP is then functionalized with hyaluronic acid (HA) to produce the HA‐FcP radical complex, thereby developing a novel, highly efficient, sensitive, long‐lasting, and low‐heavy‐metal‐content radical contrast agent for targeted imaging of ...
Xiao Huang, Yuanyuan Zhao, Miao Zhou, Yukang Guo, Haiyun Wang, Yuanyuan Chen, Jian Peng   +6 more
wiley   +1 more source

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

Advanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang, Yining Sun, Xintong Yu, Ruoqi Wang, Yuting Zhang, Jinjie Yu, Shuang Xie, Yujia Cai, Yuhong Luo, Wei Chen   +9 more
wiley   +1 more source

Parapsoriasis en Plaques Treated with Calciferol [PDF]

, 1948
H. W. Barber, David Erskine
openalex   +1 more source

Use of High-Risk Coronary Atherosclerotic Plaque Detection for Risk Stratification of Patients With Stable Chest Pain: A Secondary Analysis of the PROMISE Randomized Clinical Trial

JAMA cardiology, 2018
M. Ferencik, T. Mayrhofer, D. Bittner, H. Emami, S. Puchner, Michael T. Lu, N. Meyersohn, A. Ivanov, Elizabeth C. Adami, M. Patel, D. Mark, J. Udelson, Kerry L Lee, P. Douglas, U. Hoffmann   +14 more
semanticscholar   +1 more source

USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity

Advanced Science, EarlyView.
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang, Shan Huang, Yan He, Weiwei Wang, Chao Tong, Mengru Ma, Manyu Zhao, Lian Yi, Klaus‐Peter Knobeloch, Peijing Zhang   +9 more
wiley   +1 more source

STUDIES ON THE CHEMICAL COMPOSITION OF NORMAL AND ABNORMAL BLOOD VESSEL WALLS: 3. LOW ANGLE X-RAY DIFFRACTION STUDIES ON THE LIPID COMPONENTS IN ATHEROMATOUS PLAQUES

, 1955
J.B. Finean
openalex   +1 more source

Les cultures en stries pour remplacer les cultures sur plaques [PDF]

, 1929
R. BURRI
openalex   +1 more source