Results 251 to 260 of about 1,146,198 (394)

Real-world insight on apremilast therapy in patients with plaque psoriasis: Indian experience

, 2020
Dhiraj Dhoot, Abhishek De, Sudip Das, Aarti Sarda   +3 more
openalex   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

APM⁺ macrophages associated with plaque vulnerability via MIF-CD74 signaling: a multi-omics study. [PDF]

Hum Genomics
Xu X, Li Y, Xiang S, Liu X, Li R, Zheng B.   +5 more
europepmc   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

Carotenoid biosynthesis drives root plasticity through aerenchyma and iron plaque formation in rice. [PDF]

Nat Plants
Shrestha JK, Lin CY, Wang JY, Tang IC, Hu CH, Tsednee M, Zhang Y, Jamil M, Berqdar L, Blilou I, Al-Babili S, Wang CS, Yeh KC.   +12 more
europepmc   +1 more source

Relationship of Serum Inflammatory Biomarkers With Plaque Inflammation Assessed by FDG PET/CT

, 2013
Raphaël Duivenvoorden, Venkatesh Mani, Mark Woodward, David Kallend, Gabriela Suchánková, Valentı́n Fuster, James H.F. Rudd, Ahmed Tawakol, Michael E. Farkouh, Zahi A. Fayad   +9 more
openalex   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Missing tissue, missing data: Resolving brain volume loss caused by anti-amyloid therapies. [PDF]

PLoS Med
Alves F, Ayton S.
europepmc   +1 more source

Coronary Artery Calcium and Carotid Artery Intima Media Thickness and Plaque: Clinical Use in Need of Clarification

, 2016
Maryam Zaid, Akira Fujiyoshi, Aya Kadota, Robert D. Abbott, Katsuyuki Miura   +4 more
openalex   +2 more sources

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source