Results 261 to 270 of about 1,082,648 (349)

Comparative pathogenicity of vaccinia virus and mpox virus infections in CAST/EiJ mice: Exploring splenomegaly and transcriptomic profiles

Animal Models and Experimental Medicine, EarlyView.
We successfully constructed CAST/EiJ mice models infected with low‐dose vaccinia virus (VACV‐L), high‐dose VACV (VACV‐H), and mpox virus (MPXV), demonstrating that VACV‐L and MPXV infections induced splenomegaly in mice, and VACV‐H infection caused mortality in mice.
Yongzhi Hou, Jianrong Ma, Baoying Huang, Na Li, Lin Zhu, Ziqing Jia, Jiasen Yang, Jingjing Zhang, Wenjie Tan, Jing Xue   +9 more
wiley   +1 more source

Carbohydrates in action: influencing infection and amplification of Staphylococcus aureus bacteriophages. [PDF]

BMC Microbiol
Vadym P, Volodymyr S.
europepmc   +1 more source

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

Animal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling, Xilan Dong, Liyan Mao, Chengjun Huang, Linjing Cong, Haizeng Zhang, Jun Cai, Zhenzhen Chen   +7 more
wiley   +1 more source

Acute coronary syndromes: mechanisms, challenges, and new opportunities. [PDF]

Eur Heart J
Kraler S, Mueller C, Libby P, Bhatt DL.
europepmc   +1 more source

Asymptomatic erythematous plaque

Indian Dermatology Online Journal, 2015
Dirk M. Elston, John R. Griffin, Olga Udovenko   +2 more
openaire   +4 more sources

Building a Culture of Care in Laboratory Animal Science through practicing “remembrance”: A reflection on local practices in Sri Lanka

Animal Models and Experimental Medicine, EarlyView.
This flowchart shows how remembrance activities create space for emotional reflection, helping individuals respect and acknowledge their feelings about working with lab animals, and enhance team commitment to improve lab animal welfare. This emotional awareness can reduce compassion fatigue fueled by cultural and religious beliefs and promote human ...
A. D. D. S. Amarasekara, K. A. A. U. Karunarathna, W. M. K. M. Ratnayake, A. A. I. Senevirathne, P. Yapa, M. Gunatilake   +5 more
wiley   +1 more source

AI in Neurology: Everything, Everywhere, All at Once Part 3: Surveillance, Synthesis, Simulation, and Systems

Annals of Neurology, EarlyView.
This final part 3 review builds on the practical applications discussed in part 2 and explores how artificial intelligence (AI) is transforming data management, neurological education, and neurological care across large healthcare networks and datasets. The review also highlights AI's role in real‐world and synthetic data, digital twins, and innovative
Matthew Rizzo
wiley   +1 more source