Results 261 to 270 of about 1,146,198 (394)

MG-HGLNet: A Mixed-Grained Hierarchical Geometric-Semantic Learning Framework with Dynamic Prototypes for Coronary Artery Lesions Assessment. [PDF]

Bioengineering (Basel)
Wang X, Chen Y, Wu Y, Zhou Y, Chen Y, Feng Q.   +5 more
europepmc   +1 more source

Detection of Unstable Plaques in Patients with Carotid Stenosis Using B-Mode Ultrasonography

, 2000
Eiki Kobayashi, Junichi Ono, Sakyo Hirai, Iwao Yamakami, Noboru Saeki, A Yamaura   +5 more
openalex   +2 more sources

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Reliable in vivo intravascular imaging plaque characterization: A challenge unmet

, 2019
Anantharaman Ramasamy, Patrick W. Serruys, Daniel A. Jones, Tom Johnson, Ryo Torii, Sean Madden, Rajiv Amersey, Rob Krams, Andreas Baumbach, Anthony Mathur, Christos V. Bourantas   +10 more
openalex   +2 more sources

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

Advanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Xiaofei Li, Shenghang Wang, Shijian Ding, Sifan Yu, Huarui Zhang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Xianghang Luo, Tao Zhang, Shu Zhang, Péter Ferdinandy, Yu Huang, Daqing Ma, Aiping Lu, Baoting Zhang, Ge Zhang   +27 more
wiley   +1 more source

Advances in the Diagnosis and Management of High-Risk Cardiovascular Conditions: Biomarkers, Intracoronary Imaging, Artificial Intelligence, and Novel Anticoagulants. [PDF]

J Cardiovasc Dev Dis
Dall'Orto CC, Lopes RPF, Pinto GV, Braga PGS, da Silva MR.   +4 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Senescence as a Driver of Smooth Muscle Cell Plasticity and Atherosclerosis: Mechanisms and Therapeutic Opportunities. [PDF]

Cells
Steegen L, Grootaert MOJ.
europepmc   +1 more source

Hypoxia in Plaque Macrophages

, 2014
Ismail Sergin, Trent D. Evans, Somashubhra Bhattacharya, Babak Razani   +3 more
openalex   +1 more source

Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology.

Circulation, 1994
C. Allard, van, der Wal, A. Becker, M. Chris, der Loos, P. Das   +6 more
semanticscholar   +1 more source