Results 61 to 70 of about 1,082,648 (349)
The role of biomechanics in the assessment of carotid atherosclerosis severity: a numerical approach [PDF]
Numerical fluid biomechanics has been proved to be an efficient tool for understanding vascular diseases including atherosclerosis. There are many evidences that atherosclerosis plaque formation and rupture are associated with blood flow ...
Bou-said, Benyebka+4 more
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Serial intravascular ultrasound assessment of coronary atherosclerosis progression and remodeling [PDF]
Cardiovascular disease is a major cause of morbidity and mortality in countries with western lifestyle. Reliable quantitative assessment of the extent of coronary atherosclerosis during the natural history of coronary artery disease and following ...
Hartmann, Marc
core +3 more sources
The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability
Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability.
Tiewei Li+5 more
semanticscholar +1 more source
Can Carotid Plaque Predict Coronary Plaque?
Atherothrombotic occlusive vascular disease is a leading cause of acute cardiovascular events (acute coronary syndromes, sudden death, and ischemic stroke). Therapeutic lifestyle modification, medical therapy to control risk factors, and, in selected cases, revascularization by percutaneous ...
openaire +3 more sources
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler+43 more
wiley +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source
Endothelial to mesenchymal transition (EndMT) plays a major role during development, and also contributes to several adult cardiovascular diseases. Importantly, mesenchymal cells including fibroblasts are prominent in atherosclerosis, with key functions ...
S. Evrard+20 more
semanticscholar +1 more source
Cardiovascular diseases are still the primary causes of mortality in the United States and in Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and precipitates an acute vascular event, which is responsible for the high mortality rate.
Vancraeynest, D+4 more
openaire +4 more sources
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen+4 more
wiley +1 more source
Differential Features of Culprit Intracranial Atherosclerotic Lesions: A Whole-Brain Vessel Wall Imaging Study in Patients With Acute Ischemic Stroke. [PDF]
BackgroundIntracranial atherosclerotic disease tends to affect multiple arterial segments. Using whole-brain vessel wall imaging, we sought to study the differences in plaque features among various types of plaques in patients with a recent unilateral ...
Bi, Xiaoming+12 more
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