Results 61 to 70 of about 1,082,648 (349)

The role of biomechanics in the assessment of carotid atherosclerosis severity: a numerical approach [PDF]

open access: yes, 2018
Numerical fluid biomechanics has been proved to be an efficient tool for understanding vascular diseases including atherosclerosis. There are many evidences that atherosclerosis plaque formation and rupture are associated with blood flow ...
Bou-said, Benyebka   +4 more
core  

Serial intravascular ultrasound assessment of coronary atherosclerosis progression and remodeling [PDF]

open access: yes, 2008
Cardiovascular disease is a major cause of morbidity and mortality in countries with western lifestyle. Reliable quantitative assessment of the extent of coronary atherosclerosis during the natural history of coronary artery disease and following ...
Hartmann, Marc
core   +3 more sources

The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability

open access: yesMediators of Inflammation, 2020
Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability.
Tiewei Li   +5 more
semanticscholar   +1 more source

Can Carotid Plaque Predict Coronary Plaque?

open access: yesJACC: Cardiovascular Imaging, 2013
Atherothrombotic occlusive vascular disease is a leading cause of acute cardiovascular events (acute coronary syndromes, sudden death, and ischemic stroke). Therapeutic lifestyle modification, medical therapy to control risk factors, and, in selected cases, revascularization by percutaneous ...
openaire   +3 more sources

Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age‐ and BMI‐Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler   +43 more
wiley   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry   +2 more
wiley   +1 more source

Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

open access: yesNature Communications, 2016
Endothelial to mesenchymal transition (EndMT) plays a major role during development, and also contributes to several adult cardiovascular diseases. Importantly, mesenchymal cells including fibroblasts are prominent in atherosclerosis, with key functions ...
S. Evrard   +20 more
semanticscholar   +1 more source

Imaging the Vulnerable Plaque

open access: yesJournal of the American College of Cardiology, 2011
Cardiovascular diseases are still the primary causes of mortality in the United States and in Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and precipitates an acute vascular event, which is responsible for the high mortality rate.
Vancraeynest, D   +4 more
openaire   +4 more sources

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

open access: yesAdvanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen   +4 more
wiley   +1 more source

Differential Features of Culprit Intracranial Atherosclerotic Lesions: A Whole-Brain Vessel Wall Imaging Study in Patients With Acute Ischemic Stroke. [PDF]

open access: yes, 2018
BackgroundIntracranial atherosclerotic disease tends to affect multiple arterial segments. Using whole-brain vessel wall imaging, we sought to study the differences in plaque features among various types of plaques in patients with a recent unilateral ...
Bi, Xiaoming   +12 more
core  

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