Results 41 to 50 of about 368,495 (267)

The relation between atherosclerosis plaque composition and plaque rupture

Journal of Medical Signals & Sensors, 2020
Intima, media, and adventitia are three layers of arteries. They have different structures and different mechanical properties. Damage to intima layer of arteries leads to an inflammatory response, which is usually the reason for atherosclerosis plaque formation. Atherosclerosis plaques mainly consist of smooth muscle cells and calcium. However, plaque
Parto Babaniamansour, Maryam Mohammadi, Sepideh Babaniamansour, Ehsan Aliniagerdroudbari   +3 more
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Understanding the Matrix: The Role of Extracellular DNA in Oral Biofilms

Frontiers in Oral Health, 2021
Dental plaque is the key etiological agent in caries formation and the development of the prevalent chronic oral inflammatory disease, periodontitis.
Hannah J. Serrage, Mark A. Jepson, Nadia Rostami, Nicholas S. Jakubovics, Angela H. Nobbs   +4 more
doaj   +1 more source

Plaque regression and plaque stabilisation in cardiovascular diseases

Indian Journal of Endocrinology and Metabolism, 2013
Atherosclerosis is characterized by formation of plaques on the inner walls of arteries that threatens to become the leading cause of death worldwide via its sequelae of myocardial infarction and stroke. Endothelial dysfunction leads to cholesterol uptake and accumulation of inflammatory markers within the plaque.
Tarun Dave, J Ezhilan, Hardik Vasnawala, Vinod Somani   +3 more
openaire   +3 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Scientific and methodical development of biotechnological production of immunobiological preparations for instant diagnosis of infectious diseases and detection of pathogens

Биопрепараты: Профилактика, диагностика, лечение, 2018
The present article describes the scientific and methodological development of biotechnological manufacture of test-system components (diagnostic preparations) for instant diagnosis of plague, brucellosis, tularemia, anthrax, cholera.
I. S. Tyumentseva, I. V. Zharnikova, E. N. Afanasiev, V. I. Efremenko, O. I. Kogotkova, S. M. Kalnoy, A. N. Kulichenko   +6 more
doaj  

Construction and verification of a nomogram prediction model for vascular plaque stability in patients with progressive cerebral infarction based on serum MCP-1, MCPIP1 combined with inflammatory factors

陆军军医大学学报
Objective‍　‍To construct and validate a nomogram-based prediction model of vascular plaque stability in patients with progressive cerebral infarction based on serum monocyte chemotactic protein-1 (MCP-1), monocyte chemotactic protein-1 inducible protein ...
LI Yanda, SONG Yan, CHEN Yalun
doaj   +1 more source

Can Carotid Plaque Predict Coronary Plaque?

JACC: Cardiovascular Imaging, 2013
Atherothrombotic occlusive vascular disease is a leading cause of acute cardiovascular events (acute coronary syndromes, sudden death, and ischemic stroke). Therapeutic lifestyle modification, medical therapy to control risk factors, and, in selected cases, revascularization by percutaneous ...
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

后循环症状性急性缺血性卒中患者椎基底动脉几何形态与基底动脉斑块的HR-VWI分析 HR-VWI Analysis of Vertebrobasilar Artery Geometric Shapes and Basilar Artery Plaques in Patients with Symptomatic Acute Ischemic Stroke in the Posterior Circulation

Zhongguo cuzhong zazhi
目的 利用高分辨率血管壁成像（high resolution vessel wall imaging，HR-VWI）研究后循环症状性急性缺血性卒中（acute ischemic stroke，AIS）患者椎基底动脉（vertebrobasilar artery，VBA）几何形态与基底动脉（basilar artery，BA）斑块的发生、分布及特征之间的关系。 方法 回顾性连续纳入2017年6月—2021年12月在深圳市宝安区人民医院神经内科住院治疗的后循环症状性AIS患者，根据HR ...
钟丽玲，徐棣豪，宋建勋，林国辉，符念霞 (ZHONG Liling, XU Dihao, SONG Jianxun, LIN Guohui, FU Nianxia )
doaj   +1 more source