Results 131 to 140 of about 3,405,475 (294)

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

open access: yesAdvanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen   +11 more
wiley   +1 more source

Glassell Hall Bench Plaque

open access: yes, 1993
This image was taken by Rebecca Vandewalle '12.Plaque inscription: "Gift of the Class of 1993"This plaque is located on a ...

core  

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen   +5 more
wiley   +1 more source

Evaluation of zinc as an adjunct in chlorhexidine containing toothpaste on gingival and plaque index

open access: yesJournal of Oral Health and Oral Epidemiology, 2017
BACKGROUND AND AIM: Bacterial plaque is the uppermost element in periodontal diseases. Chlorhexidine (CHX) is one of the utmost influential materials in chemical plaque control and ORTHOKIN is a toothpaste claimed to encompass CHX.
Mohadeseh Arabsolghar   +2 more
doaj  

Ultrasonic and clinical risk factors of solitary Plaque-RADS-2 carotid plaque for predicting anterior circulation ischemic stroke

open access: yesFrontiers in Cardiovascular Medicine
BackgroundPlaque-RADS-2 carotid plaque is regarded as a low risk for attribution of cerebrovascular events. Nevertheless, in individuals with carotid plaque, the risk of ischemic stroke poses a continuous threat to both health and quality of life.
Shuangshuang Zhao   +10 more
doaj   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang   +9 more
wiley   +1 more source

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

open access: yesAdvanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong   +13 more
wiley   +1 more source

Plaque from Student Government Association at State University of New York - Cortland

open access: yes, 2012
A replica of the plaque was hung in their student union ...
State University of New York at Cortland
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