Results 111 to 120 of about 3,405,475 (294)

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Effect of 20-ppm ozone and 1% chlorhexidine gels on plaque index and Streptococcus mutans counts in the dental plaque in 6-12-year-old children: A randomized, double-blind clinical trial. [PDF]

J Dent Res Dent Clin Dent Prospects, 2023
Adhami ZE, Erfanparast L, Molaei Z, Sadeghi J, Yazdanparas A.   +4 more
europepmc   +1 more source

EFFECT OF PROBIOTICS AND PROPOLIS ON PLAQUE INDEX, PLAQUE PH, AND SALIVARY PH VALUES

Journal of IMAB - Annual Proceeding (Scientific Papers)
Introduction: Despite preventive care, the prevalence of dental caries worldwide remains significant. This requires the search for and expansion of options for its prevention. Part of this effort is the addition of probiotic bacteria and propolis to various products for use in the oral cavity to reduce pathogenic microorganisms.
Ralitsa Bogovska-Gigova, Krasimir Hristov   +1 more
openaire   +2 more sources

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ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

Systematic Review and Meta Analysis of the Relative Effect on Plaque Index among Pediatric Patients Using Powered (Electric) versus Manual Toothbrushes. [PDF]

Dent J (Basel), 2023
Graves A, Grahl T, Keiserman M, Kingsley K.   +3 more
europepmc   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Electric and Manual Oral Hygiene Routines Affect Plaque Index Score Differently. [PDF]

Int J Environ Res Public Health, 2021
Bahammam S, Chen CY, Ishida Y, Hayashi A, Ikeda Y, Ishii H, Kim DM, Nagai S.   +7 more
europepmc   +1 more source

A Blood‐Derived Double‐Network Hydrogel with Robust Wet Adhesion for Keratinized Mucosa Regeneration via Neutrophil Phenotype Reprogramming and Mechanophysical Niche Modulation

Advanced Science, EarlyView.
The iPRF‐MA/Alg‐NHS/Lut@EGCG (PGAE) double‐network hydrogel achieves durable wet adhesion in the oral environment. It simultaneously reprograms neutrophils from NETosis to phagocytosis for biofilm clearance, and activates the FAK‐RhoA‐YAP mechanotransduction pathway in gingival fibroblasts to drive extracellular matrix remodeling, thereby promoting ...
Sicong Ren, Xinting Yang, Jingxia Chen, Yihan Wang, Jian Feng, Jing Zhou, Jiaxin Luo, Jingjie Zhai, Quan Lin, Yanmin Zhou   +9 more
wiley   +1 more source

Periodontal condition in relation to nutritional status among kindergarten children in Al-Ramadi city/Iraq

Journal of Baghdad College of Dentistry, 2014
Background: Nutrition can affect periodontal disease through contributing to microbial growth in the gingival crevice, affecting the immunological response to bacterial antigens and assisting the repair mechanism of the connective tissue at the local ...
Inaam M Suhail, Wesal Al-Obaidi
doaj