Results 91 to 100 of about 234,795 (273)
Comparison of serum TNF-α, IL-6, and IL-8 between thick and thin plaque psoriasis.
, 2015 Serum levels of TNF-α were not significantly different (p = 0.11), but its downstream cytokines, IL-6 and IL-8, were significantly higher in thick plaque psoriasis compared to thin plaque psoriasis (p = 0.0035 for IL-6, p = 0.0036 for IL-8) for a mixed ...
Mayte Suárez-Fariñas (27734) +6 more
core +1 more source
Nail Psoriasis in Pediatric Populations
JEADV Clinical Practice, EarlyView.ABSTRACT Pediatric nail psoriasis is an under‐recognized yet clinically important manifestation of psoriasis with both diagnostic and prognostic implications. Nail involvement in children is associated with greater overall disease severity, poorer treatment outcomes, and is a predictor for the development of psoriatic arthritis.
Aditya K. Gupta +3 more
wiley +1 more source
Ustekinumab in the therapy of chronic plaque psoriasis
, 2009 Jenna L O’Neill, Robert E KalbState University of New York at Buffalo, School of Medicine and Biomedical Sciences, Department of Dermatology, NY, USAAbstract: Psoriasis is a chronic inflammatory disorder characterized by T cell dysregulation ...
Jenna L O’Neill, Robert E Kalb
core
According to European guidelines and the Diagnostic and Therapeutic Recommendations of the Polish Dermatological Society (Polskiego Towarzystwa Dermatologicznego, PTD), the therapeutic goal of the treatment of plaque psoriasis is currently full or almost
Adam Reich +8 more
core +1 more source
Real World Use of the IL‐36 Receptor Antagonist Spesolimab: A Systematic Review and Analysis
JEADV Clinical Practice, EarlyView.ABSTRACT Background Spesolimab, an interleukin‐36 receptor antagonist, is approved for the treatment and prevention of generalised pustular psoriasis (GPP) flares. Its use has increasingly been reported in real‐world settings for both GPP and other inflammatory dermatoses.
Sophia A. Mense +4 more
wiley +1 more source
Psoriasis: Classical vs. Paradoxical. The Yin-Yang of TNF and Type I Interferon
Frontiers in Immunology, 2018 Chronic plaque psoriasis is a common debilitating skin disease. The identification of the pathogenic role of the TNF/IL-23/TH17 pathway has enabled the development of targeted therapies used in the clinic today. Particularly, TNF inhibitors have become a
Alessio Mylonas, Curdin Conrad
doaj +1 more source
Comparison of psoriasis transcriptome scores between thick and thin plaque psoriasis.
, 2015 Based on psoriasis transcriptome references, psoriasis transcriptome scores are calculated by the combined z-score gene set variation analysis (GSVA) method.
Mayte Suárez-Fariñas (27734) +6 more
core +1 more source
Phytotherapy Research, EarlyView.Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko +3 more
wiley +1 more source
Prevalence of metabolic syndrome in patients with psoriasis: a population-based study in the United Kingdom. [PDF]
, 2012 Increasing epidemiological evidence suggests independent associations between psoriasis and cardiovascular and metabolic disease. Our objective was to test the hypothesis that directly assessed psoriasis severity relates to the prevalence of metabolic ...
Troxel, Andrea B +15 more
core +1 more source