Results 181 to 190 of about 234,795 (273)

Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

open access: yesArthritis &Rheumatology, Volume 78, Issue 11, Page 2261-2273, November 2026.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher   +12 more
wiley   +1 more source

A Rapid and Marked Response to Guselkumab in Extensive Plaque Psoriasis: A Case Report. [PDF]

open access: yesCureus
Oropesa E   +5 more
europepmc   +1 more source

Beyond Pigmentation: Interplay of Metabolic Profile, Carotid Intima—Media Thickness, and Fatty Liver in Vitiligo: An Age‐ and Sex‐Matched Case‐Control Study

open access: yesHealth Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Vitiligo shares inflammatory and metabolic pathways with cardiovascular and hepatic steatosis. Carotid intima–media thickness (IMT) is an established marker of early subclinical atherosclerosis, whereas non‐alcoholic fatty liver disease (NAFLD) reflects hepatic involvement in chronic inflammatory and metabolic dysregulation.
Mehrdad Mozafar   +8 more
wiley   +1 more source

Efficacy and Safety of the First Adalimumab Biosimilar in Chinese Children with Severe Plaque Psoriasis: The PISCES Study, a Multicenter Prospective Study. [PDF]

open access: yesDermatol Ther (Heidelb)
Huang Y   +15 more
europepmc   +1 more source

Triggering of Koebner Phenomenon by Picosecond Laser in a Psoriatic Patient: Clinical and Immunopathologic Insights

open access: yesLasers in Surgery and Medicine, Volume 58, Issue 9, Page 745-749, November 2026.
ABSTRACT Objectives To report the first case of Koebner phenomenon induced by picosecond laser treatment in a patient with psoriasis. We analyzed the clinical and histopathological features and discussed the possible mechanism by which the laser's photomechanical effect triggered the reaction.
Teppei Sakai, Koya Sonoda, Jun Omatsu
wiley   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang   +4 more
wiley   +1 more source

Erythematous Pustular Plaques in a Child

open access: yes
Pediatric Dermatology, EarlyView.
Nicole Kah Mun Yoong   +2 more
wiley   +1 more source

Discoid Lupus Erythematosus in Genital Skin: A Case Report and Review of the Literature

open access: yesJournal of Cutaneous Pathology, Volume 53, Issue 11, Page 1000-1006, November 2026.
ABSTRACT Background Discoid lupus erythematosus (DLE) represents the most common variant of chronic cutaneous lupus erythematosus, a skin‐specific autoimmune disorder within the broader lupus erythematosus spectrum Clinically, DLE is characterized by erythematous, scaly plaques with areas of hyperpigmentation.
Ala' Abu‐Dayeh   +2 more
wiley   +1 more source

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