Results 61 to 70 of about 234,795 (273)

Successful Co‐Administration of Secukinumab and Dupilumab in a Patient With Psoriasis and Paradoxical Atopic Dermatitis

JEADV Clinical Practice, EarlyView.
ABSTRACT Paradoxical atopic dermatitis (AD) can arise during biologic therapy for psoriasis due to an immune‐axis imbalance. We describe a 47‐year‐old man who developed severe AD while receiving secukinumab, which was successfully managed with the addition of dupilumab, allowing long‐term control of both diseases.
So Yun Park, Minjung Park, Ho Eun Gwang, Narang Hong, Hye Jung Jung, Mi Youn Park, Jiyoung Ahn   +6 more
wiley   +1 more source

Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency

JEADV Clinical Practice, EarlyView.
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz, Lars Matthies, Andrea Vanegas Ramirez   +2 more
wiley   +1 more source

Polymorphisms in the PTPN22 region are associated with psoriasis of early onset [PDF]

, 2008
Background: Psoriasis, a chronic inflammatory skin disease, affects approximately 2% of the population worldwide. Although the aetiology of psoriasis is poorly understood, patients with disease of early onset (Type I, age of onset ≤ 40 years) usually ...
Gittins, M P, Strachan, D., Eyre, S, Young, H S, Barker, J N W N, Worthington, J., Strachan, D, Smith, R L, McArdle, W., Eyre, S.; id_orcid, Griffiths, C. E M, Ke, X., Warren, RB, Griffiths, CE, Gittins, M. P.; id_orcid, Warren, R B, Worthington, J, Warren, Richard, Allen, M., Ke, X, Gittins, MP, McArdle, W, Griffths, C E M, Young, HS, Smith, RL, Barker, JN, Allen, M, Smith, R. Ll, Barker, J. N W N, Young, H. S., Warren, Richard; id_orcid   +30 more
core   +1 more source

DERMACLEAR: AI‐Powered Insights Into Four Chronic Inflammatory Skin Diseases in Spain

JEADV Clinical Practice, EarlyView.
Using an AI‐enhanced analysis of electronic health records from nearly 50,000 patients, the DERMACLEAR study provides real‐world insights into the prevalence, clinical complexity, comorbidities and treatment patterns of HS, CU, PsO and AD in Spain.
Ana Giménez‐Arnau, Javier Ortiz de Frutos, Raquel Rivera‐Díaz, Lluís Puig, Jaume Notario Rosa, José Luis López‐Estebaranz, Vicente García‐Patos Briones, Ana Martín‐Santiago, José Ignacio Rojo‐Laguna, Elisabet Fernández‐Martínez, Lara Gómez‐Labrador, Esteban Daudén   +11 more
wiley   +1 more source

Lichen planopilaris coexisting with plaque psoriasis effectively treated with brodalumab

, 2020
Lichen planopilaris coexisting with plaque psoriasis effectively treated with ...
Maurelli M, Girolomoni G, Colato C, Tessari G   +3 more
core   +1 more source

Paradoxical Alopecia Areata Induced by IL‐17 and IL‐23 Inhibitors: A Systematic Review

JEADV Clinical Practice, EarlyView.
This systematic review identifies consistent clinical patterns of alopecia areata associated with IL‐17 and IL‐23 inhibitors, most frequently involving secukinumab and ustekinumab. Disease severity varied widely, and management often required biologic discontinuation or therapeutic switching.
Isabella Kamholtz, Simonetta I. Gaumond, Joaquin J. Jimenez   +2 more
wiley   +1 more source

Potential role of ixekizumab in the treatment of moderate-to-severe plaque psoriasis

Clinical, Cosmetic and Investigational Dermatology, 2013
Vicky Ren,1 Harry Dao Jr2 1Baylor College of Medicine , School of Medicine, 2Department of Dermatology, Baylor College of Medicine Houston, TX, USA Background: Psoriasis is a debilitating autoimmune skin disease that affects 2%–3% of the world ...
Ren V, Dao Jr H
doaj  

Treatment of pro-B acute lymphoblastic leukemia and severe plaque psoriasis with anti-CD19 CAR T cells: a case report

Frontiers in Immunology
We report on a rare case of adult pro-B acute lymphoblastic leukemia (pro-B ALL) accompanied with severe refractory plaque psoriasis treated using autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy.
Ao Zhang, Ao Zhang, Guangji Zhang, Guangji Zhang, Huihui Yang, Huihui Yang, Bengfa Gong, Bengfa Gong, Shouyun Li, Shouyun Li, Na Wei, Na Wei, Hui Xue, Hui Xue, Hui Wei, Hui Wei, Jianxiang Wang, Jianxiang Wang, Shaowei Qiu, Shaowei Qiu   +19 more
doaj   +1 more source

Narrow-band UVB phototherapy does not consistently improve quality of life in psoriasis patients: A prospective observational study from Eastern India

Indian Dermatology Online Journal, 2018
Introduction: Psoriasis is a chronic inflammatory and proliferative condition of the skin which is well-known to impair the patients' quality of life (QoL).
Shweta Arora, Bikash R Kar
doaj   +1 more source

Quality of life in patients with mild plaque psoriasis

, 2023
Objective To investigate the influence of mild psoriasis on the quality of patients' lives. Methods Based on PASI score and quality of life index, a questionnaire was designed to investigate the quality of lives in aspects of physiology, psychology ...
Bin YANG, Xiaoyu QIU, Mudiao CHEN, Xiaohua WANG, Peizhen ZHAO   +4 more
core   +1 more source