Results 101 to 110 of about 700,142 (373)
Brain Pathology, Volume 33, Issue 1, January 2023., 2023 Schematic depicting characterization of pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in neurodegenerative diseases. Abstract Accumulation of pathological tau aggregates is a prominent feature in tauopathies that leads during the course of the diseases to neuronal dysfunction before and cell death after ...
Mauro Montalbano +4 more
wiley +1 more source
Cardiovascular Diabetology, 2021 Background Apolipoprotein (Apo) A1 and Apo B are strongly associated with the risk of atherosclerotic cardiovascular disease (ASCVD). However, the relationship between the Apo B/A1 ratio and the morphology of coronary vulnerable plaques has not been ...
Fuxue Deng +8 more
doaj +1 more source
From prevention to plaque rupture and infarction [PDF]
European Heart Journal, 2015 ![Graphic][1] Statins are a cornerstone of cardiovascular prevention and are highly recommended in current guidelines.1 However, statin-associated muscle symptoms are one of the principal reasons for statin non-adherence and/or discontinuation,2 contributing to adverse cardiovascular outcomes. The issue contains a timely Consensus Paper by Erik S.G.
openaire +3 more sources
Morphologic Features of Carotid Plaque Rupture Assessed by Optical Coherence Tomography
American Journal of Neuroradiology, 2015 BACKGROUND AND PURPOSE: Rupture of the plaque fibrous cap and subsequent thrombosis are the major causes of stroke. This study evaluated morphologic features of plaque rupture in the carotid artery by using optical coherence tomography in vivo. MATERIALS
Seigo Shindo +8 more
semanticscholar +1 more source
Annals of Neurology, EarlyView.Objective The Clarity AD phase III trial showed that lecanemab reduced amyloid markers in early Alzheimer's disease (AD) and resulted in less decline on measures of cognition and function than placebo. Herein, we aimed to characterize amyloid‐β (Aβ) protofibril (PF) captured by lecanemab in human cerebrospinal fluid (CSF) from living participants with ...
Moeko Noguchi‐Shinohara +8 more
wiley +1 more source
BMC Cardiovascular Disorders, 2012 Background This study characterizes the distribution and components of plaque structure by presenting a three-dimensional blood-vessel modelling with the aim of determining mechanical properties due to the effect of lipid core and calcification within a ...
Wong Kelvin KL +4 more
doaj +1 more source
Efficient Parallel Simulation of Atherosclerotic Plaque Formation Using Higher Order Discontinuous Galerkin Schemes [PDF]
arXiv, 2014 The compact Discontinuous Galerkin 2 (CDG2) method was successfully tested for elliptic problems, scalar convection-diffusion equations and compressible Navier-Stokes equations. In this paper we use the newly developed DG method to solve a mathematical model for early stages of atherosclerotic plaque formation.
arxiv
A new lipid-structured model to investigate the opposing effects of LDL and HDL on atherosclerotic plaque macrophages [PDF]
arXiv, 2022 Atherosclerotic plaques form in artery walls due to a chronic inflammatory response driven by lipid accumulation. A key component of the inflammatory response is the interaction between monocyte-derived macrophages and extracellular lipid. Although concentrations of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles in the blood
arxiv
Plaque Rupture: Plaque Stress, Shear Stress, and Pressure Drop
Journal of the American College of Cardiology, 2008 We read with interest the article by Fukumoto et al. ([1][1]) in a previous issue of the Journal . They used 3-dimensional intravascular ultrasound and computational fluid dynamics (CFD) to study wall shear stress (WSS) distribution in arteries with ruptured plaques.
Li, Zhi Yong, Gillard, Jonathan H.
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British Educational Research Journal, EarlyView.Abstract This paper explores the growing influence of young people's activism in UK museums and its educational implications. It draws on a five‐year collaborative programme (2019–2023) with young people of colour (16–28) in a university museum setting, focusing on a Young Collective established to address cultural inequalities.
Sadia Habib
wiley +1 more source