Results 101 to 110 of about 755,810 (388)

New insights into fibrous cap thickness of vulnerable plaques assessed by optical coherence tomography

BMC Cardiovascular Disorders, 2022
Objective Vulnerable plaques with fibrous cap thickness (FCT) of ≤65 μm are prone to rupture and/or thrombosis. However, plaques with FCT > 65 μm cause acute myocardial infarction and even sudden death. We aimed to investigate the relationship between 65 
Xianglan Liu, Wujian He, Xulin Hong, Duanbin Li, Zhezhe Chen, Yao Wang, Zhaoyang Chen, Yi Luan, Wenbin Zhang   +8 more
doaj   +1 more source

Gene deficiency in activating Fcγ receptors influences the macrophage phenotypic balance and reduces atherosclerosis in mice [PDF]

, 2013
Immunity contributes to arterial inflammation during atherosclerosis. Oxidized low-density lipoproteins induce an autoimmune response characterized by specific antibodies and immune complexes in atherosclerotic patients.
Egido, J., Gomez-Guerrero, C., Lazaro, I., Lopez-Franco, O., Lopez-Parra, V., Lutgens, E., Mallavia, B., Oguiza, A., Ortiz-Muñoz, G., Recio, C.   +9 more
core   +5 more sources

Morphologic Features of Carotid Plaque Rupture Assessed by Optical Coherence Tomography

American Journal of Neuroradiology, 2015
BACKGROUND AND PURPOSE: Rupture of the plaque fibrous cap and subsequent thrombosis are the major causes of stroke. This study evaluated morphologic features of plaque rupture in the carotid artery by using optical coherence tomography in vivo. MATERIALS
Seigo Shindo, K. Fujii, M. Shirakawa, K. Uchida, Y. Enomoto, T. Iwama, M. Kawasaki, Yukio Ando, S. Yoshimura   +8 more
semanticscholar   +1 more source

From prevention to plaque rupture and infarction [PDF]

European Heart Journal, 2015
![Graphic][1] Statins are a cornerstone of cardiovascular prevention and are highly recommended in current guidelines.1 However, statin-associated muscle symptoms are one of the principal reasons for statin non-adherence and/or discontinuation,2 contributing to adverse cardiovascular outcomes. The issue contains a timely Consensus Paper by Erik S.G.
openaire   +3 more sources

Putative Murine Models of Plaque Rupture [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2007
To be useful, animal models for human diseases must be well defined.1 Thus we are concerned that investigators will be mislead by the definitions and terminology used by Jackson et al1a to describe putative plaque rupture models in mice. We are especially concerned with their use of “acute plaque rupture” to describe murine lesions that do not mimic ...
Falk, Erling, Schwartz, Stephen M, Galis, Zorina S, Rosenfeld, Michael E   +3 more
openaire   +2 more sources

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

Advanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

Effect of calcification on the mechanical stability of plaque based on a three-dimensional carotid bifurcation model

BMC Cardiovascular Disorders, 2012
Background This study characterizes the distribution and components of plaque structure by presenting a three-dimensional blood-vessel modelling with the aim of determining mechanical properties due to the effect of lipid core and calcification within a ...
Wong Kelvin KL, Thavornpattanapong Pongpat, Cheung Sherman CP, Sun Zhonghua, Tu Jiyuan   +4 more
doaj   +1 more source

Plaque Rupture: Plaque Stress, Shear Stress, and Pressure Drop

Journal of the American College of Cardiology, 2008
We read with interest the article by Fukumoto et al. ([1][1]) in a previous issue of the Journal . They used 3-dimensional intravascular ultrasound and computational fluid dynamics (CFD) to study wall shear stress (WSS) distribution in arteries with ruptured plaques.
Li, Zhi Yong, Gillard, Jonathan H.
openaire   +7 more sources

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Colchicine therapy in acute coronary syndrome patients acts on caspase-1 to suppress NLRP3 inflammasome monocyte activation [PDF]

, 2016
Inflammasome activation, with subsequent release of pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18, has recently been implicated in atherosclerosis-associated inflammation. This study aims to assess in acute coronary syndrome (ACS) patients (
Christina Bursill, Cloe A Payet, David S Celermajer, Gonzalo J Martínez, Jennifer Y Barraclough, Sanjay Patel, Stacy Robertson, † ‡, † ‡   +8 more
core   +1 more source