Results 201 to 210 of about 700,142 (373)

Tissue-engineered collagenous fibrous cap models to systematically elucidate atherosclerotic plaque rupture. [PDF]

Sci Rep, 2022
Wissing TB, Van der Heiden K, Serra SM, Smits AIPM, Bouten CVC, Gijsen FJH.   +5 more
europepmc   +1 more source

Sterol imbalances and cholesterol‐24‐hydroxylase dysregulation is linked to the underlying progression of multiple sclerosis

Brain Pathology, EarlyView.
We have sought to determine the role that cholesterol metabolism plays in disability worsening and its correlation with progressive MS by analysing patient CSF and post‐mortem tissues using cutting edge mass spectrometry approaches. Key sterol metabolites measured in the CSF link with important disability milestones at the very early stages of MS ...
Lauren Griffiths, Kristen Hawkins, Eylan Yutuc, Roberto Angelini, Racheal Fosuah, Manuela Pacciarini, Alison Dickson, Neil Robertson, Laura Childs, Samantha Loveless, Emma Tallantyre, William J. Griffiths, Yuqin Wang, Owain W. Howell   +13 more
wiley   +1 more source

Stroke induces early recurrent vascular events by inflammasome-dependent atherosclerotic plaque rupture

, 2023
Liesz A, Cao J, Roth S, Zhang S, Kopczak A, Georgakis M, Li X, Dutsch A, Liman T, Endres M, Brough D, Green J, Wernsdorf S, Fürle C, Carofiglio O, Zhu J, Asare Y, Group DS, Dichgans M, Sager H, Grosse G.   +20 more
europepmc   +2 more sources

Diagnostic Performance of 60 MHz High-Definition Intravascular Ultrasound versus Fourier Domain Optical Coherence Tomography for Identifying Plaque Rupture, Plaque Erosion, and Thrombosis in a Rabbit Model. [PDF]

Rev Cardiovasc Med, 2023
Wang G, Qiao W, Xing C, Yao Z, Sun Y, Huang X, Wang X, Liu Q, Zhang R, Luo X, Yu Y, Dai J, Hou J, Yu B.   +13 more
europepmc   +1 more source

Molecular Markers, Fibrous Cap Rupture, and the Vulnerable Plaque [PDF]

, 2001
Stephen M. Schwartz, Thomas S. Hatsukami, Chun Yuan   +2 more
openalex   +1 more source

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

Brain Pathology, EarlyView.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie, Michael J. Miller, Celine Hardy, Ava R. Jarvis, Timothy F. Czajka, Lianna D'Brant, Natasha Rugenstein, Adam Waickman, Eain Murphy, David C. Butler   +9 more
wiley   +1 more source

TNF-α is a Novel Biomarker for Predicting Plaque Rupture in Patients with ST-Segment Elevation Myocardial Infarction. [PDF]

J Inflamm Res, 2022
Luo X, Zhao C, Wang S, Jia H, Yu B.
europepmc   +1 more source

Introductory remarks of symposium on “The consequences from initial atherosclerotic lesion to plaque rupture”

, 1998
Toshiharu Ishii
openalex   +2 more sources

Quantitative T1 is sensitive to cortical remyelination in multiple sclerosis: A postmortem MRI study

Brain Pathology, EarlyView.
In a post‐mortem study using multiparametric qMRI of whole fixed human brains from people with multiple sclerosis (pwMS), we found evidence that quantitative T1 (qT1) is sensitive to remyelination in the cortex. In contrast, QSM and radial diffusivity were affected by cortical pathology independently of remyelination. Our data suggest that qT1 could be
Riccardo Galbusera, Matthias Weigel, Erik Bahn, Sabine Schaedelin, Alessandro Cagol, Po‐Jui Lu, Muhamed Barakovic, Lester Melie‐Garcia, Jonas Franz, Peter Dechent, Govind Nair, Ludwig Kappos, Wolfgang Brück, Christine Stadelmann, Cristina Granziera   +14 more
wiley   +1 more source

Efficacy of IDOR‐1117‐2520, a novel, orally available CCR6 antagonist in preclinical models of skin dermatitis

British Journal of Pharmacology, EarlyView.
Background and Purpose The chemokine receptor CCR6 guides pathogenic T17 cells, implicated in autoimmune diseases including psoriasis, to sites of inflammation via the chemokine CCL20. Therefor, pharmacological inhibition of CCR6+ immune cell migration provides a novel therapeutic approach.
Paulina Kulig, Pijus Brazauskas, Madeleine Suffiotti, Emilie Raoult, Ulrike Babilonski, Bérengère Renault, Ursula Grieder, Enrico Vezzali, Peter Blattmann, Marianne M. Martinic, Mark J. Murphy   +10 more
wiley   +1 more source