Results 201 to 210 of about 755,810 (388)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Sphingosine-1-Phosphate (S1P) Lyase Inhibition Aggravates Atherosclerosis and Induces Plaque Rupture in ApoE^-/-Mice. [PDF]

Int J Mol Sci, 2022
Keul P, Peters S, von Wnuck Lipinski K, Schröder NH, Nowak MK, Duse DA, Polzin A, Weske S, Gräler MH, Levkau B.   +9 more
europepmc   +1 more source

Nonculprit Plaque Characteristics in Patients With Acute Coronary Syndrome Caused by Plaque Erosion vs Plaque Rupture: A 3-Vessel Optical Coherence Tomography Study

JAMA cardiology, 2018
T. Sugiyama, Erika Yamamoto, K. Bryniarski, Lei Xing, Hang Lee, M. Isobe, P. Libby, I. Jang   +7 more
semanticscholar   +1 more source

Investigating Strain Rate Effects on the Anisotropic Mechanical Properties of Lignin‐Filled Glass/Polypropylene Long‐Fiber Thermoplastics Manufactured via Direct Compounded Compression Molding (LFT‐D)

Polymer Composites, EarlyView.
Strain rate effect on lignin‐filled glass/PP LFT composites showing enhanced tensile strength and microstructural response at elevated loading rates. ABSTRACT Fiber‐reinforced composites are employed in various sectors, such as the transportation sector, where they are subjected to various loading conditions, including high loading rates. In this study,
Tarun Khapra, Thanh Dat Vo, Reza Beigpour, Sajjad Dehghanpour, W. Altenhof   +4 more
wiley   +1 more source

A Novel Monocyte Subset as a Unique Signature of Atherosclerotic Plaque Rupture. [PDF]

Front Cell Dev Biol, 2021
Vinci R, Pedicino D, Bonanni A, D'Aiello A, Severino A, Pisano E, Ponzo M, Canonico F, Ciampi P, Russo G, Di Sario M, Montone RA, Trani C, Conte C, Grimaldi MC, Cribari F, Massetti M, Crea F, Liuzzo G.   +18 more
europepmc   +1 more source

Phytochemical Nanoparticles for the Treatment of Neurological Disorders

Phytochemical Analysis, EarlyView.
ABSTRACT Neurological disorders impose a significant burden on the healthcare systems. The latest published data by WHO indicated that stroke was the second leading cause of death globally in 2020, with Alzheimer's disease (AD) and other dementias in the seventh position.
Touraj Ehtezazi, Satyajit D. Sarker
wiley   +1 more source

Tissue-engineered collagenous fibrous cap models to systematically elucidate atherosclerotic plaque rupture. [PDF]

Sci Rep, 2022
Wissing TB, Van der Heiden K, Serra SM, Smits AIPM, Bouten CVC, Gijsen FJH.   +5 more
europepmc   +1 more source

Metalloproteinase production from macrophages – a perfect storm leading to atherosclerotic plaque rupture and myocardial infarction

Experimental Physiology, 2016
A. Newby
semanticscholar   +1 more source

Focal extracorporeal shockwave therapy in shoulder calcific tendinopathy: A retrospective observational study of sonographic prognostic factors

PM&R, EarlyView.
Abstract Objective To assess the potential prognostic role of sonographic parameters such as glenohumeral joint effusion, subacromial‐subdeltoid bursitis, and the type of intratendinous calcific deposition to predict the clinical and functional outcomes of focal extracorporeal shockwave therapy (fESWT) in patients with calcific tendinopathy of the ...
Arianna Pesaresi, Vincenzo Ricci, Giacomo Farì, Danilo Donati, Ke‐Vin Chang, Fabrizio Gervasoni, Levent Özçakar   +6 more
wiley   +1 more source

Stroke induces early recurrent vascular events by inflammasome-dependent atherosclerotic plaque rupture

, 2023
Liesz A, Cao J, Roth S, Zhang S, Kopczak A, Georgakis M, Li X, Dutsch A, Liman T, Endres M, Brough D, Green J, Wernsdorf S, Fürle C, Carofiglio O, Zhu J, Asare Y, Group DS, Dichgans M, Sager H, Grosse G.   +20 more
europepmc   +2 more sources