Results 51 to 60 of about 755,810 (388)

CT attenuation analysis of carotid intraplaque hemorrhage [PDF]

, 2018
Background and Purpose: Intraplaque hemorrhage is considered a leading parameter of carotid plaque vulnerability. Our purpose was to assess the CT characteristics of intraplaque hemorrhage with histopathologic correlation to identify features that allow ...
Bassareo, P. P., Cecco, C. N. D., Faa, X. G., Francone, M., Lai, L., Montisci, R., Saba, L., Sanfilippo, Rosa, Suri, J. S.   +8 more
core   +1 more source

Management and Outcome of Patients With Acute Coronary Syndrome Caused by Plaque Rupture Versus Plaque Erosion: An Intravascular Optical Coherence Tomography Study

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background Plaque rupture and erosion are the 2 most common mechanisms for acute coronary syndromes. However, the outcome of these 2 distinct pathologies in patients with acute coronary syndromes has never been studied.
Sining Hu, Yinchun Zhu, Yingying Zhang, J. Dai, Lulu Li, H. Dauerman, T. Soeda, Zhao Wang, Hang Lee, Chao Wang, C. Zhe, Yan Wang, G. Zheng, Shaosong Zhang, H. Jia, Bo Yu, I. Jang   +16 more
semanticscholar   +1 more source

Myocardial Bridge and Acute Plaque Rupture [PDF]

Journal of Investigative Medicine High Impact Case Reports, 2016
A myocardial bridge (MB) is a common anatomic variant, most frequently located in the left anterior descending coronary artery, where a portion of the coronary artery is covered by myocardium. Importantly, MBs are known to result in a proximal atherosclerotic lesion.
Jennifer A. Tremmel, Alan C. Yeung, David V. Daniels, Leor Perl, Shige Tanaka, Ingela Schnittger, Jonathan G. Schwartz   +6 more
openaire   +4 more sources

Combined imaging, computational and histological analysis of a ruptured carotid plaque: A patient-specific analysis

Artery Research, 2010
Background: Rupture of carotid plaques is an important cause of cerebrovascular events. Several factors, including wall shear stress (WSS), plaque morphology and peak cap stress, have been associated with plaque vulnerability.
Giulia Soloperto, Niall G. Keenan, Mary N. Sheppard, Jacques Ohayon, Nigel B. Wood, Dudley J. Pennell, Raad H. Mohiaddin, Xiao Yun Xu   +7 more
doaj   +1 more source

Differences between the Molecular Mechanisms Underlying Ruptured and Non-Ruptured Carotid Plaques, and the Significance of ABCA1 [PDF]

Journal of Stroke, 2018
Background and Purpose Carotid plaques are a strong risk factor for ischemic stroke, and plaque rupture poses an even higher risk. Although many studies have investigated the pathogenic mechanisms of carotid plaque formation, few have studied the ...
Sung Hyuk Heo, Eun-Hye Lee, Hyun-Hee Park, Bum Joon Kim, Hyo Chul Youn, Young Seo Kim, Hyun Young Kim, Seong-Ho Koh, Dae-Il Chang   +8 more
doaj   +1 more source

Prevalence of Healed Plaque and Factors Influencing Its Characteristics Under Optical Coherence Tomography in Patients With Coronary Artery Disease: A Systematic Review, Meta-Analysis, and Meta-Regression

Frontiers in Cardiovascular Medicine, 2021
Aim: The purpose of this study was to determine the prevalence of healed plaque and its characteristics under optical coherence tomography (OCT) through a formal systematic review, meta-analysis, and meta-regression.Methods and Results: Thirteen studies ...
Xunxun Feng, Yang Liu, Jiaqi Yang, Guangyao Zhai, Yujie Zhou, Qianyun Guo   +5 more
doaj   +1 more source

Focal adhesions as mechanosensors: the two-spring model [PDF]

, 2004
Adhesion-dependent cells actively sense the mechanical properties of their environment through mechanotransductory processes at focal adhesions, which are integrin-based contacts connecting the extracellular matrix to the cytoskeleton.
Schwarz, Ulrich S., Erdmann, Thorsten, Bischofs, Ilka B.   +2 more
core   +2 more sources

Circulating microRNAs as potential biomarkers for coronary plaque rupture

OncoTarget, 2017
Coronary plaque rupture is the most common cause of acute coronary syndrome. However, the timely biomarker-based diagnosis of plaque rupture remains a major unmet clinical challenge.
Sufang Li, Chongyou Lee, Jun-xian Song, Changlin Lu, Jun Liu, Yuxia Cui, Huizhu Liang, Chengfu Cao, Feng Zhang, Hong Chen   +9 more
semanticscholar   +1 more source

Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release [PDF]

, 2017
Aims: Calcium phosphate (CaP) particle deposits are found in several inflammatory diseases including atherosclerosis and osteoarthritis. CaP, and other forms of crystals and particles, can promote inflammasome formation in macrophages leading to caspase ...
Afonina, Alexander N. Kapustin, Alfaidi, Bailet, Baroja-Mazo, Bautista Nino, Bennett, Burton, Catherine M. Shanahan, Chen, Cilla, Coopman, Cossetti, Cullen, Cunningham, Dautova, Diane Proudfoot, Duewell, Ehara, Erlinge, Ewence, Feil, Fuerst, Furman, Gross, Hanneke Okkenhaug, Hendriks, Hilgendorf, Hutcheson, Irkle, Iyemere, Jin, Kalra, Kapustin, Kevin Pappert, Kistowska, Krisenko, Laliberte, LaRocca, Lau, Li, Liu, Liu, Luga, Maldonado, Martin, Martin D. Bootman, Matthias Epple, Mfunyi, Migita, Mocsai, Molloy, Morgan, Nadra, Nakahara, Narayan, Ng, Pazar, Piccioli, Pugliese, Qu, Ragnauth, Ridker, Ruiz, Scimeca, Shamaa, Simon J. Cook, Smith, Song, Swaan, Vengrenyuk, Vigano, Virmani, Wang, Webber, Yana Dautova, Young   +76 more
core   +2 more sources

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source