Results 31 to 40 of about 47,117 (196)

Ultra-short echo time cardiovascular magnetic resonance of atherosclerotic carotid plaque [PDF]

, 2010
Background Multi-contrast weighted cardiovascular magnetic resonance (CMR) allows detailed plaque characterisation and assessment of plaque vulnerability.
Sonia Nielles-Vallespin, Nielles-Vallespin, S, Firmin, DN, Chan, Cheuk F, Keenan, Niall G, Mary N Sheppard, Gatehouse, Peter, Chan Cheuk F, Firmin David N, Gatehouse, P, Keenan, NG, Sheppard, MN, Boyle, JJ, Peter Gatehouse, Chan, CF, Sheppard Mary N, Boyle Joseph J, Joseph J Boyle, Niall G Keenan, Nielles-Vallespin, Sonia, Boyle, Joseph J, Sheppard, Mary N, Pennell, Dudley J, Pennell, DJ, Pennell Dudley J, Gatehouse Peter, Dudley J Pennell, Nielles-Vallespin Sonia, David N Firmin, Cheuk F Chan, Keenan Niall G, Firmin, David N   +31 more
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Morphological and Stress Vulnerability Indices for Human Coronary Plaques and Their Correlations with Cap Thickness and Lipid Percent: An IVUS-Based Fluid-Structure Interaction Multi-patient Study. [PDF]

PLoS Computational Biology, 2015
Plaque vulnerability, defined as the likelihood that a plaque would rupture, is difficult to quantify due to lack of in vivo plaque rupture data. Morphological and stress-based plaque vulnerability indices were introduced as alternatives to obtain ...
Liang Wang, Jie Zheng, Akiko Maehara, Chun Yang, Kristen L Billiar, Zheyang Wu, Richard Bach, David Muccigrosso, Gary S Mintz, Dalin Tang   +9 more
doaj   +1 more source

Studying the Factors of Human Carotid Atherosclerotic Plaque Rupture, by Calculating Stress/Strain in the Plaque, Based on CEUS Images: A Numerical Study

Frontiers in Neuroinformatics, 2020
Carotid plaque neovascularization is one of the major factors for the classification of vulnerable plaque, but the axial force effects of the pulsatile blood flow on the plaque with neovessel and intraplaque hemorrhage was unclear.
Zhenzhou Li, Yongfeng Wang, Xinyin Wu, Xin Liu, Shanshan Huang, Yi He, Shuyu Liu, Lijie Ren   +7 more
doaj   +1 more source

A novel workflow combining plaque imaging, plaque and plasma proteomics identifies biomarkers of human coronary atherosclerotic plaque disruption

Clinical Proteomics, 2017
Background Atherosclerotic plaque rupture is the culprit event which underpins most acute vascular syndromes such as acute myocardial infarction. Novel biomarkers of plaque rupture could improve biological understanding and clinical management of ...
Regent Lee, Roman Fischer, Philip D. Charles, David Adlam, Alessandro Valli, Katalin Di Gleria, Rajesh K. Kharbanda, Robin P. Choudhury, Charalambos Antoniades, Benedikt M. Kessler, Keith M. Channon   +10 more
doaj   +1 more source

Travelling to Rome : inflammation, endoplasmic reticulum stress and angiogenesis during atherosclerotic plaque development [PDF]

, 2010
Cardiovascular diseases are the leading cause of death worldwide followed by cancer. Atherosclerosis, the major underlying cause of cardiovascular diseases, is a syndrome affecting medium-sized and large arteries.
Kyriakakis, Emmanouil
core   +1 more source

Mean platelet volume and coronary plaque vulnerability: an optical coherence tomography study in patients with non-ST-elevation acute coronary syndrome

BMC Cardiovascular Disorders, 2019
Background The association between mean platelet volume (MPV) and coronary plaque vulnerability in patients with non-ST-elevation ACS (NSTE-ACS) has not been investigated.
Jun Wang, Xing Li, Jun Pu, Siyu Jin, Lu Jia, Xiaomei Li, Fen Liu, Yining Yang   +7 more
doaj   +1 more source

Combined imaging, computational and histological analysis of a ruptured carotid plaque: A patient-specific analysis

Artery Research, 2010
Background: Rupture of carotid plaques is an important cause of cerebrovascular events. Several factors, including wall shear stress (WSS), plaque morphology and peak cap stress, have been associated with plaque vulnerability.
Giulia Soloperto, Niall G. Keenan, Mary N. Sheppard, Jacques Ohayon, Nigel B. Wood, Dudley J. Pennell, Raad H. Mohiaddin, Xiao Yun Xu   +7 more
doaj   +1 more source

Sonodynamic Therapy Suppresses Neovascularization in Atherosclerotic Plaques via Macrophage Apoptosis-Induced Endothelial Cell Apoptosis

JACC: Basic to Translational Science, 2020
Summary: During atherosclerosis plaque progression, pathological intraplaque angiogenesis leads to plaque rupture accompanied by thrombosis, which is probably the most important cause of arteries complications such as cerebral and myocardial infarction ...
Jianting Yao, MD, PhD, Weiwei Gao, MD, Yu Wang, MD, PhD, Lu Wang, PhD, Kamal Diabakte, MD, Jinyang Li, MD, Jiemei Yang, MD, Yongxing Jiang, MD, Yuerong Liu, MD, Shuyuan Guo, MD, Xuezhu Zhao, MD, Zhengyu Cao, MD, Xi Chen, MD, PhD, Qiannan Li, MD, Haiyu Zhang, PhD, Wei Wang, MD, Zhen Tian, PhD, Bicheng Li, MD, PhD, Fang Tian, MD, PhD, Guodong Wu, MD, Shirin Pourteymour, PhD, Xi Huang, MD, Fancheng Tan, MD, Xiaoru Cao, MD, Zhuowen Yang, MD, Kang Li, PhD, Yan Zhang, PhD, Yong Li, MD, PhD, Zhiguo Zhang, PhD, Hong Jin, MD, PhD, Ye Tian, MD, PhD   +30 more
doaj   +1 more source

Differences between the Molecular Mechanisms Underlying Ruptured and Non-Ruptured Carotid Plaques, and the Significance of ABCA1 [PDF]

Journal of Stroke, 2018
Background and Purpose Carotid plaques are a strong risk factor for ischemic stroke, and plaque rupture poses an even higher risk. Although many studies have investigated the pathogenic mechanisms of carotid plaque formation, few have studied the ...
Sung Hyuk Heo, Eun-Hye Lee, Hyun-Hee Park, Bum Joon Kim, Hyo Chul Youn, Young Seo Kim, Hyun Young Kim, Seong-Ho Koh, Dae-Il Chang   +8 more
doaj   +1 more source

Increases of Corporal Temperature as a Risk Factor of Atherosclerotic Plaque Instability

, 2008
This work explores for the first time the effects of temperature increments on the development of high shear stresses between plaque and arterial wall due to their different dilatational properties. Data from the literature report febrile reactions prior
Rojo Pérez, Francisco Javier, Elices, Margarita L., Gonzalez, Pablo, Ortega Pozzi, Aranzazu, Elices Calafat, Manuel, Torres Coronado, Monica, Guinea Tortuero, Gustavo V., Fantidis, Panayotis, Atienza Riera, José Miguel, Hayashi, Kozaburo   +9 more
core   +1 more source