Results 31 to 40 of about 374,414 (247)

Combined imaging, computational and histological analysis of a ruptured carotid plaque: A patient-specific analysis

Artery Research, 2010
Background: Rupture of carotid plaques is an important cause of cerebrovascular events. Several factors, including wall shear stress (WSS), plaque morphology and peak cap stress, have been associated with plaque vulnerability.
Giulia Soloperto, Niall G. Keenan, Mary N. Sheppard, Jacques Ohayon, Nigel B. Wood, Dudley J. Pennell, Raad H. Mohiaddin, Xiao Yun Xu   +7 more
doaj   +1 more source

Sonodynamic Therapy Suppresses Neovascularization in Atherosclerotic Plaques via Macrophage Apoptosis-Induced Endothelial Cell Apoptosis

JACC: Basic to Translational Science, 2020
Summary: During atherosclerosis plaque progression, pathological intraplaque angiogenesis leads to plaque rupture accompanied by thrombosis, which is probably the most important cause of arteries complications such as cerebral and myocardial infarction ...
Jianting Yao, MD, PhD, Weiwei Gao, MD, Yu Wang, MD, PhD, Lu Wang, PhD, Kamal Diabakte, MD, Jinyang Li, MD, Jiemei Yang, MD, Yongxing Jiang, MD, Yuerong Liu, MD, Shuyuan Guo, MD, Xuezhu Zhao, MD, Zhengyu Cao, MD, Xi Chen, MD, PhD, Qiannan Li, MD, Haiyu Zhang, PhD, Wei Wang, MD, Zhen Tian, PhD, Bicheng Li, MD, PhD, Fang Tian, MD, PhD, Guodong Wu, MD, Shirin Pourteymour, PhD, Xi Huang, MD, Fancheng Tan, MD, Xiaoru Cao, MD, Zhuowen Yang, MD, Kang Li, PhD, Yan Zhang, PhD, Yong Li, MD, PhD, Zhiguo Zhang, PhD, Hong Jin, MD, PhD, Ye Tian, MD, PhD   +30 more
doaj   +1 more source

Differences between the Molecular Mechanisms Underlying Ruptured and Non-Ruptured Carotid Plaques, and the Significance of ABCA1 [PDF]

Journal of Stroke, 2018
Background and Purpose Carotid plaques are a strong risk factor for ischemic stroke, and plaque rupture poses an even higher risk. Although many studies have investigated the pathogenic mechanisms of carotid plaque formation, few have studied the ...
Sung Hyuk Heo, Eun-Hye Lee, Hyun-Hee Park, Bum Joon Kim, Hyo Chul Youn, Young Seo Kim, Hyun Young Kim, Seong-Ho Koh, Dae-Il Chang   +8 more
doaj   +1 more source

Prevalence of Healed Plaque and Factors Influencing Its Characteristics Under Optical Coherence Tomography in Patients With Coronary Artery Disease: A Systematic Review, Meta-Analysis, and Meta-Regression

Frontiers in Cardiovascular Medicine, 2021
Aim: The purpose of this study was to determine the prevalence of healed plaque and its characteristics under optical coherence tomography (OCT) through a formal systematic review, meta-analysis, and meta-regression.Methods and Results: Thirteen studies ...
Xunxun Feng, Yang Liu, Jiaqi Yang, Guangyao Zhai, Yujie Zhou, Qianyun Guo   +5 more
doaj   +1 more source

Coronary Plaque Characteristics and Underlying Mechanism of Acute Coronary Syndromes in Different Age Groups of Patients With Diabetes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background High cardiovascular mortality has been reported in young patients with diabetes. However, the underlying pathology in different age groups of patients with diabetes has not been studied.
Keishi Suzuki, Takayuki Niida, Haruhito Yuki, Daisuke Kinoshita, Daichi Fujimoto, Hang Lee, Iris McNulty, Masamichi Takano, Sunao Nakamura, Tsunekazu Kakuta, Kyoichi Mizuno, Ik‐Kyung Jang   +11 more
doaj   +1 more source

The detection of carotid plaque rupture caused by intraplaque hemorrhage by serial high-resolution magnetic resonance imaging: a case report. [PDF]

, 2008
BACKGROUND: Plaque rupture is believed to be a critical event that leads to thromboembolic complications in atherosclerotic carotid artery disease. Intraplaque hemorrhage can also cause fibrous cap disruption and may be related to the progression of ...
Nagata, Izumi, Nakamoto, Morito, Tsutsumi, Keisuke, Morikawa, Minoru, Hayashi, Kentaro, Kawahara, Ichiro, Kitagawa, Naoki, Hayashi, Tomayoshi   +7 more
core   +1 more source

Coronary Atherosclerosis Imaging

Diagnostics, 2020
Identifying patients at increased risk of coronary artery disease, before the atherosclerotic complications become clinically evident, is the aim of cardiovascular prevention.
Michael Y. Henein, Sergio Vancheri, Gani Bajraktari, Federico Vancheri   +3 more
doaj   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Numerical investigation of atherosclerotic plaque rupture using optical coherence tomography imaging and XFEM [PDF]

, 2018
Myocardial infarction contributes to most fatalities in which atherosclerotic plaque disruption is the underlying pathology. From the mechanics view point, the pulsatile blood flow in the arteries resembles a fatigue environment and generates stresses ...
Yarlagadda, Prasad K.D.V., Wang, Jiaqiu, Gu, YuanTong, Paritala, Phani Kumari, Li, Zhiyong   +4 more
core   +1 more source

Investigation for atherosclerotic plaque rupture with thrombosis in mice based on single-cell sequencing and bioinformatics analysis

Frontiers in Cardiovascular Medicine
IntroductionAtherosclerotic plaque rupture with thrombus formation leads to severe cardiovascular events. We hoped to explore the hub genes providing critical roles in the process of atherosclerotic plaque rupture accompanied by thrombus formation, which
Peng Nie, Fang Wan, Tianbao Yao, Yao Li, Guofeng Yan, Jun Pu, Shuxuan Jin   +6 more
doaj   +1 more source