Visualization of Vulnerable Coronary Plaque and Prevention of Plaque Rupture. [PDF]
Juntendo Iji ZasshiIn daily clinical practice, assessing anatomical findings and the presence or absence of ischemia is pivotal for determining the need for percutaneous coronary intervention. However, concurrently, comprehending vulnerability can greatly assist in predicting future cardiovascular events and formulating preventive strategies for individual patients. This
Fukase T, Dohi T.
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Mechanisms of plaque vulnerability and rupture
Journal of the American College of Cardiology, 2003 Rupture of atherosclerotic plaque has been identified as the proximate event in the majority of cases of acute ischemic syndromes. Plaque rupture exposes thrombogenic components of the plaque, activating the clotting cascade and promoting thrombus formation.
Shah, Prediman K.
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Developing a novel rabbit model of atherosclerotic plaque rupture and thrombosis by cold-induced endothelial injury [PDF]
Journal of Biomedical Science, 2009 Background It is widely believed that atherosclerotic plaque rupture and subsequent thrombosis leads to acute coronary events and stroke. However, study of the mechanism and treatment of human plaque rupture is hampered by lack of a suitable animal model.
Jiang Zhi-Xin +2 more
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Plaque Rupture, Compared With Plaque Erosion, Is Associated With a Higher Level of Pancoronary Inflammation [PDF]
JACC: Cardiovascular Imaging, 2022 Damini Dey, Hang Lee, Taishi Yonetsu
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Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Acute Myocardial Infarction
Frontiers in Immunology, 2022 BackgroundAcute myocardial infarction (AMI) can occur in patients with atherosclerotic disease, with or without plaque rupture. Previous studies have indicated a set of immune responses to plaque rupture.
Jun Qian +14 more
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Frontiers in Cardiovascular Medicine, 2022 ObjectivesPlaque vulnerability and rupture rather than plaque size are the major cause of clinical events in patients with intermediate coronary lesions.
Jintong Jiang +6 more
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Tissue characteristics of residual lesion in patients with acute coronary syndrome caused by plaque rupture versus plaque erosion: a single-center, retrospective, observational study. [PDF]
Nagoya J Med SciPatients with acute coronary syndrome (ACS), frequently caused by plaque rupture (PR), often have vulnerable plaques in residual lesions as well as in culprit lesions.
Suzuki W +10 more
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Mechanisms of Plaque Formation and Rupture [PDF]
Circulation Research, 2014 Atherosclerosis causes clinical disease through luminal narrowing or by precipitating thrombi that obstruct blood flow to the heart (coronary heart disease), brain (ischemic stroke), or lower extremities (peripheral vascular disease). The most common of these manifestations is coronary heart disease, including stable angina pectoris and the acute ...
Bentzon, Jacob Fog; id_orcid 0000-0002-3020-5002 +3 more
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Ruptured plaque or embolised thrombus [PDF]
Heart, 2004 A 38 year old woman with acute chest pain was admitted to the hospital. Positive troponins and electrocardiographic signs of anterior wall myocardial infarction during atrial fibrillation were found. Echocardiography (panel below) showed hypokinesia of the anterior wall and severe mitral stenosis (arrowhead; LV, left ventricle; SC, spontaneous contrast)
J, Van der Heyden +2 more
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Numerical investigation of atherosclerotic plaque rupture using optical coherence tomography imaging and XFEM [PDF]
, 2018 Myocardial infarction contributes to most fatalities in which atherosclerotic plaque disruption is the underlying pathology. From the mechanics view point, the pulsatile blood flow in the arteries resembles a fatigue environment and generates stresses ...
Yarlagadda, Prasad K.D.V. +4 more
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