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Atherosclerotic Plaque Rupture [PDF]
It is generally established that the unstable plaque is the major cause of acute clinical sequelae of atherosclerosis. Unfortunately, terms indicating lesions prone to plaque instability, such as “vulnerable plaque,” and the different phenotypes of unstable plaques, such as plaque rupture, plaque fissuring, intraplaque hemorrhage, and erosion, are ...
Esther, Lutgens +8 more
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Carotid plaque stress analysis by fluid structure interaction based on in-vivo MRI: Implications to plaque vulnerability assessment [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 2010.Stroke is one of the leading causes of death in the world, resulting mostly from the sudden rupture of atherosclerotic plaques.
Gao, Hao
core +8 more sources
Mechanisms of plaque vulnerability and rupture [PDF]
Rupture of atherosclerotic plaque has been identified as the proximate event in the majority of cases of acute ischemic syndromes. Plaque rupture exposes thrombogenic components of the plaque, activating the clotting cascade and promoting thrombus formation.
Shah, Prediman K.
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Carotid plaque vulnerability assessment by microscopic morphology analysis, ultrasound and 3D model reconstruction [PDF]
This thesis was submitted for the degree of Docter of Philosophy and awarded by Brunel University.Research suggests that plaque morphology plays a crucial role in determining plaque vulnerability.
Choudhury, Ahsan
core +7 more sources
Plaque Rupture in Humans and Mice [PDF]
Despite the many studies of murine atherosclerosis, we do not yet know the relevance of the natural history of this model to the final events precipitated by plaque disruption of human atherosclerotic lesions. The literature has become particularly confused because of the common use of terms such as “instability”, “vulnerable”, “rupture”, or even ...
Schwartz, Stephen M +3 more
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Ruptured plaque or embolised thrombus [PDF]
A 38 year old woman with acute chest pain was admitted to the hospital. Positive troponins and electrocardiographic signs of anterior wall myocardial infarction during atrial fibrillation were found. Echocardiography (panel below) showed hypokinesia of the anterior wall and severe mitral stenosis (arrowhead; LV, left ventricle; SC, spontaneous contrast)
J, Van der Heyden +2 more
openaire +2 more sources
Background: The metabolism of hyaluronan (HA) is widely known to be involved in the process of acute coronary syndrome, but it is unknown how circulating HA levels change in ST-Segment–Elevation Myocardial Infarction (STEMI) patients and whether HA is ...
Jiannan Li +12 more
doaj +1 more source
The Time-Dependent Role of Bisphosphonates on Atherosclerotic Plaque Calcification
Atherosclerotic plaque calcification directly contributes to the leading cause of morbidity and mortality by affecting plaque vulnerability and rupture risk.
Amirala Bakhshian Nik +6 more
doaj +1 more source
Can OCT change the therapeutic strategy in ACS due to plaque erosion?
The pathophysiology of acute coronary syndromes was thought to be coronary thrombosis over a plaque rupture. Autopsy studies revealed that not all cases were due to plaque rupture, even denuded endothelium or calcific nodule can beget a thrombus ...
I. Sathyamurthy, G. Sengottuvelu
doaj +1 more source
Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression. [PDF]
The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that ...
Margreet R de Vries +5 more
doaj +1 more source

