Results 11 to 20 of about 42,323 (259)
Biomechanics and inflammation in atherosclerotic plaque erosion and plaque rupture: implications for cardiovascular events in women. [PDF]
PLoS ONE, 2014 Although plaque erosion causes approximately 40% of all coronary thrombi and disproportionally affects women more than men, its mechanism is not well understood.
Ian C Campbell +7 more
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Mechanisms of Plaque Formation and Rupture [PDF]
Circulation Research, 2014 Atherosclerosis causes clinical disease through luminal narrowing or by precipitating thrombi that obstruct blood flow to the heart (coronary heart disease), brain (ischemic stroke), or lower extremities (peripheral vascular disease). The most common of these manifestations is coronary heart disease, including stable angina pectoris and the acute ...
Bentzon, Jacob Fog; id_orcid 0000-0002-3020-5002 +3 more
openaire +3 more sources
eLife, 2021 Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stress exerting this disrupting force.
Andrea Milzi +6 more
doaj +1 more source
Ruptured plaque or embolised thrombus [PDF]
Heart, 2004 A 38 year old woman with acute chest pain was admitted to the hospital. Positive troponins and electrocardiographic signs of anterior wall myocardial infarction during atrial fibrillation were found. Echocardiography (panel below) showed hypokinesia of the anterior wall and severe mitral stenosis (arrowhead; LV, left ventricle; SC, spontaneous contrast)
J, Van der Heyden +2 more
openaire +2 more sources
Cardiovascular Diabetology, 2020 Background Postprandial hyperglycemia was reported to play a key role in established risk factors of coronary artery diseases (CAD) and cardiovascular events.
Gong Su +6 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Background: The metabolism of hyaluronan (HA) is widely known to be involved in the process of acute coronary syndrome, but it is unknown how circulating HA levels change in ST-Segment–Elevation Myocardial Infarction (STEMI) patients and whether HA is ...
Jiannan Li +12 more
doaj +1 more source
Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression. [PDF]
PLoS ONE, 2012 The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that ...
Margreet R de Vries +5 more
doaj +1 more source
The Time-Dependent Role of Bisphosphonates on Atherosclerotic Plaque Calcification
Journal of Cardiovascular Development and Disease, 2022 Atherosclerotic plaque calcification directly contributes to the leading cause of morbidity and mortality by affecting plaque vulnerability and rupture risk.
Amirala Bakhshian Nik +6 more
doaj +1 more source
Can OCT change the therapeutic strategy in ACS due to plaque erosion?
Indian Heart Journal, 2021 The pathophysiology of acute coronary syndromes was thought to be coronary thrombosis over a plaque rupture. Autopsy studies revealed that not all cases were due to plaque rupture, even denuded endothelium or calcific nodule can beget a thrombus ...
I. Sathyamurthy, G. Sengottuvelu
doaj +1 more source
Plaque Rupture in Humans and Mice [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2007 Despite the many studies of murine atherosclerosis, we do not yet know the relevance of the natural history of this model to the final events precipitated by plaque disruption of human atherosclerotic lesions. The literature has become particularly confused because of the common use of terms such as “instability”, “vulnerable”, “rupture”, or even ...
Schwartz, Stephen M +3 more
openaire +3 more sources