Plaque Structural Stress: Detection, Determinants and Role in Atherosclerotic Plaque Rupture and Progression [PDF]
Frontiers in Cardiovascular Medicine, 2022 Atherosclerosis remains a major cause of death worldwide, with most myocardial infarctions being due to rupture or erosion of coronary plaques. Although several imaging modalities can identify features that confer risk, major adverse cardiovascular event
Sophie Z. Gu, Martin R. Bennett
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The relation between atherosclerosis plaque composition and plaque rupture [PDF]
Journal of Medical Signals and Sensors, 2020 Background: Intima, media, and adventitia are three layers of arteries. They have different structures and different mechanical properties. Damage to intima layer of arteries leads to an inflammatory response, which is usually the reason for ...
Parto Babaniamansour +3 more
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Analysis of MicroRNAs Associated With Carotid Atherosclerotic Plaque Rupture With Thrombosis [PDF]
Frontiers in Genetics, 2021 Atherosclerosis is a progressive vascular wall inflammatory disease, and the rupture of atherosclerotic vulnerable plaques is the leading cause of morbidity and mortality worldwide.
Peng Nie +4 more
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Biomechanics and inflammation in atherosclerotic plaque erosion and plaque rupture: implications for cardiovascular events in women. [PDF]
PLoS ONE, 2014 Although plaque erosion causes approximately 40% of all coronary thrombi and disproportionally affects women more than men, its mechanism is not well understood.
Ian C Campbell +7 more
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Investigation for atherosclerotic plaque rupture with thrombosis in mice based on single-cell sequencing and bioinformatics analysis [PDF]
Frontiers in Cardiovascular MedicineIntroductionAtherosclerotic plaque rupture with thrombus formation leads to severe cardiovascular events. We hoped to explore the hub genes providing critical roles in the process of atherosclerotic plaque rupture accompanied by thrombus formation, which
Peng Nie +6 more
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Study on the association between neovascularization of culprit lesions and plaque rupture in patients with acute myocardial infarction [PDF]
BMC Cardiovascular DisordersBackground Neovascularization (NV) within plaques is widely recognized as an important indicator of plaque vulnerability; however, the relationship between NV and plaque rupture in patients with acute myocardial infarction (AMI) has not been extensively ...
Long Zhang +8 more
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Identification of Carotid Artery Microstructure and Plaque Rupture Using C-Arm Cone-Beam CT: A Case Report [PDF]
Frontiers in Neurology, 2021 C-arm cone-beam computed tomography (CBCT) offers a high imaging resolution with a wide range of contrast to visualize vessels, soft tissue, and bone.
Jia Dong +15 more
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Atherosclerotic Plaque Rupture [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2003 It is generally established that the unstable plaque is the major cause of acute clinical sequelae of atherosclerosis. Unfortunately, terms indicating lesions prone to plaque instability, such as “vulnerable plaque,” and the different phenotypes of unstable plaques, such as plaque rupture, plaque fissuring, intraplaque hemorrhage, and erosion, are ...
Esther, Lutgens +8 more
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eLife, 2021 Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stress exerting this disrupting force.
Andrea Milzi +6 more
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Importance of inflammation in arteriosclerotic plaque destabilization and rupture [PDF]
Vojnosanitetski Pregled, 2005 Introduction. Although Rudolf Virchow considered arteriosclerosis an inflammatory disease in his book Cellular Pathology published in 1858, the opinion that it was a degenerative arterial disease as a civilization disease prevailed.
Tatić Vujadin +4 more
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