Results 1 to 10 of about 1,136 (118)

The relation between atherosclerosis plaque composition and plaque rupture

Journal of Medical Signals and Sensors, 2020
Background: Intima, media, and adventitia are three layers of arteries. They have different structures and different mechanical properties. Damage to intima layer of arteries leads to an inflammatory response, which is usually the reason for ...
Parto Babaniamansour, Maryam Mohammadi, Sepideh Babaniamansour, Ehsan Aliniagerdroudbari   +3 more
doaj   +3 more sources

Developing a novel rabbit model of atherosclerotic plaque rupture and thrombosis by cold-induced endothelial injury

Journal of Biomedical Science, 2009
Background It is widely believed that atherosclerotic plaque rupture and subsequent thrombosis leads to acute coronary events and stroke. However, study of the mechanism and treatment of human plaque rupture is hampered by lack of a suitable animal model.
Jiang Zhi-Xin, Zhang Qing-Hua, Fang Shun-Miao   +2 more
exaly   +3 more sources

Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Acute Myocardial Infarction

Frontiers in Immunology, 2022
BackgroundAcute myocardial infarction (AMI) can occur in patients with atherosclerotic disease, with or without plaque rupture. Previous studies have indicated a set of immune responses to plaque rupture.
Jun Qian, Yanhua Gao, Yan Lai, Zi Ye, Yian Yao, Keke Ding, Jing Tong, Hao Lin, Guoqi Zhu, Yunan Yu, Haoran Ding, Deqiang Yuan, Jiapeng Chu, Fei Chen, Xuebo Liu   +14 more
doaj   +1 more source

Analysis of MicroRNAs Associated With Carotid Atherosclerotic Plaque Rupture With Thrombosis

Frontiers in Genetics, 2021
Atherosclerosis is a progressive vascular wall inflammatory disease, and the rupture of atherosclerotic vulnerable plaques is the leading cause of morbidity and mortality worldwide.
Peng Nie, Fan Yang, Fang Wan, Shuxuan Jin, Jun Pu   +4 more
doaj   +1 more source

Association of Neutrophil to Lymphocyte Ratio With Plaque Rupture in Acute Coronary Syndrome Patients With Only Intermediate Coronary Artery Lesions Assessed by Optical Coherence Tomography

Frontiers in Cardiovascular Medicine, 2022
ObjectivesPlaque vulnerability and rupture rather than plaque size are the major cause of clinical events in patients with intermediate coronary lesions.
Jintong Jiang, Huasu Zeng, Yang Zhuo, Changqian Wang, Jun Gu, Junfeng Zhang, Huili Zhang   +6 more
doaj   +1 more source

Biomechanics and inflammation in atherosclerotic plaque erosion and plaque rupture: implications for cardiovascular events in women. [PDF]

PLoS ONE, 2014
Although plaque erosion causes approximately 40% of all coronary thrombi and disproportionally affects women more than men, its mechanism is not well understood.
Ian C Campbell, Jonathan D Suever, Lucas H Timmins, Alessandro Veneziani, Raymond P Vito, Renu Virmani, John N Oshinski, W Robert Taylor   +7 more
doaj   +1 more source

Mechanisms of Plaque Formation and Rupture [PDF]

Circulation Research, 2014
Atherosclerosis causes clinical disease through luminal narrowing or by precipitating thrombi that obstruct blood flow to the heart (coronary heart disease), brain (ischemic stroke), or lower extremities (peripheral vascular disease). The most common of these manifestations is coronary heart disease, including stable angina pectoris and the acute ...
Bentzon, Jacob Fog; id_orcid 0000-0002-3020-5002, Otsuka, Fumiyuki, Virmani, Renu, Falk, Erling   +3 more
openaire   +3 more sources

Identification of Carotid Artery Microstructure and Plaque Rupture Using C-Arm Cone-Beam CT: A Case Report

Frontiers in Neurology, 2021
C-arm cone-beam computed tomography (CBCT) offers a high imaging resolution with a wide range of contrast to visualize vessels, soft tissue, and bone.
Jia Dong, Jia Dong, Xuesong Bai, Xuesong Bai, Adam A. Dmytriw, Adam A. Dmytriw, Lanlan Xuan, Tao Wang, Tao Wang, Xia Lu, Xia Lu, Yao Feng, Yao Feng, Liqun Jiao, Liqun Jiao, Liqun Jiao   +15 more
doaj   +1 more source

Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis

eLife, 2021
Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stress exerting this disrupting force.
Andrea Milzi, Enrico Domenico Lemma, Rosalia Dettori, Kathrin Burgmaier, Nikolaus Marx, Sebastian Reith, Mathias Burgmaier   +6 more
doaj   +1 more source

Effect of 1,5-anhydroglucitol levels on culprit plaque rupture in diabetic patients with acute coronary syndrome

Cardiovascular Diabetology, 2020
Background Postprandial hyperglycemia was reported to play a key role in established risk factors of coronary artery diseases (CAD) and cardiovascular events.
Gong Su, Ming-Xi Gao, Gen-Ling Shi, Xi-Xi Dai, Wei-Feng Yao, Tao Zhang, Shao-Wei Zhuang   +6 more
doaj   +1 more source