Results 61 to 70 of about 755,810 (388)

MMP-13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation. [PDF]

, 2018
BACKGROUND: Acute thrombotic syndromes lead to atherosclerotic plaque rupture with subsequent thrombus formation, myocardial infarction and stroke. Following rupture, flowing blood is exposed to plaque components, including collagen, which triggers ...
Farndale, Richard W, Hamaia, Samir W, Howes, Joanna-Marie, Jung, Stephanie M, Knäuper, Vera, Malcor, Jean-Daniel, Pugh, Nicholas   +6 more
core   +4 more sources

Atherosclerotic Plaque Rupture: Identifying the Straw That Breaks the Camel's Back.

Arteriosclerosis, Thrombosis and Vascular Biology, 2016
The idiom “the straw that breaks the camel’s back” describes scenarios where seemingly minor incidents eventuate in a sudden, unexpected, and often detrimental downfall.
Yung-Chih Chen, A. Huang, T. Kyaw, A. Bobik, K. Peter   +4 more
semanticscholar   +1 more source

Coronary Atherosclerosis Imaging

Diagnostics, 2020
Identifying patients at increased risk of coronary artery disease, before the atherosclerotic complications become clinically evident, is the aim of cardiovascular prevention.
Michael Y. Henein, Sergio Vancheri, Gani Bajraktari, Federico Vancheri   +3 more
doaj   +1 more source

Coronary Plaque Characteristics and Underlying Mechanism of Acute Coronary Syndromes in Different Age Groups of Patients With Diabetes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background High cardiovascular mortality has been reported in young patients with diabetes. However, the underlying pathology in different age groups of patients with diabetes has not been studied.
Keishi Suzuki, Takayuki Niida, Haruhito Yuki, Daisuke Kinoshita, Daichi Fujimoto, Hang Lee, Iris McNulty, Masamichi Takano, Sunao Nakamura, Tsunekazu Kakuta, Kyoichi Mizuno, Ik‐Kyung Jang   +11 more
doaj   +1 more source

Cholesterol crystal embolization following plaque rupture: a systemic disease with unusual features

Journal of Biomedical Research, 2017
Cholesterol crystal embolic (CCE) syndrome is often a clinically challenging condition that has a poor prognostic implication. It is a result of plaque rupture with release of cholesterol crystals into the circulation that embolize into various tissue ...
Firas A. Ghanem, D. Vodnala, J. Kalavakunta, S. Durga, Noah Thormeier, P. Subramaniyam, Scott Abela, G. Abela   +7 more
semanticscholar   +1 more source

Plaque Vulnerability Index Predicts Cardiovascular Events: A Histological Study of an Endarterectomy Cohort

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The balance between stabilizing and destabilizing atherosclerotic plaque components is used in experimental studies and in imaging studies to identify rupture prone plaques.
Isabel Goncalves, Jiangming Sun, Christoffer Tengryd, Mihaela Nitulescu, Ana F. Persson, Jan Nilsson, Andreas Edsfeldt   +6 more
doaj   +1 more source

Mathematical models for vulnerable plaques [PDF]

, 2009
A plaque is an accumulation and swelling in the artery walls and typically consists of cells, cell debris, lipids, calcium deposits and fibrous connective tissue.
Bell, J., Breward, C., Chou, T., Fok, P.-W., Haugh, J. M., Li, Q., Rossi, L., Walter, A., Yang, X., Zemlyanova, A., Zhang, N.   +10 more
core  

Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study [PDF]

, 2016
Background and Purpose Carotid artery atherosclerotic plaque composition may influence plaque stability and risk of thromboembolic events, and non-invasive plaque imaging may therefore permit risk stratification for clinical management.
Condon, B., Foo, S.Y., Forbes, K.P., Holmes, W.M., Lopez Gonzalez, M.R., Muir, K.W., Stewart, W., Welch, G.   +7 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Ultra-short echo time cardiovascular magnetic resonance of atherosclerotic carotid plaque. [PDF]

, 2010
BACKGROUND: Multi-contrast weighted cardiovascular magnetic resonance (CMR) allows detailed plaque characterisation and assessment of plaque vulnerability.
Boyle, JJ, Chan, CF, Firmin, DN, Gatehouse, P, Keenan, NG, Nielles-Vallespin, S, Pennell, DJ, Sheppard, MN   +7 more
core   +2 more sources