Results 71 to 80 of about 700,142 (373)
Arthritis Care &Research, EarlyView.Objective Targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) have expanded the management of autoimmune diseases, including rheumatic diseases. As the use of these drugs grows, it is important to understand their effects on pregnancy.
Vienna Cheng +7 more
wiley +1 more source
Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics
Proteins: Structure, Function, and Bioinformatics, EarlyView., 2023 Abstract Before the controversial approval of humanized monoclonal antibody lecanemab, which binds to the soluble amyloid‐β protofibrils, all the treatments available earlier, for Alzheimer's disease (AD) were symptomatic. The researchers are still struggling to find a breakthrough in AD therapeutic medicine, which is partially attributable to lack in ...
Sharif Arar +2 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
wiley +1 more source
Skin Health and Disease, Volume 2, Issue 4, December 2022., 2022 Abstract Psoriasis is a chronic inflammatory skin condition, which can be affected by stress. Living with psoriasis can trigger negative emotions, which may influence quality of life. The present study explored the lived experiences of people with psoriasis with attention to the potential role of anger in the onset and progression of the chronic skin ...
Olivia Hughes, Rachael Hunter
wiley +1 more source
Indonesian Biomedical Journal, 2009 BACKGROUND: Thrombus is a main cause of cardiac death. Therefore identifying which coronary artery plaque is vulnerable to rupture is a critical step for cardiac intervention to prevent future cardiac events.
Tommy Heryantho +2 more
doaj +1 more source
Automated detection of vulnerable plaque in intravascular ultrasound images [PDF]
, 2018 Acute Coronary Syndrome (ACS) is a syndrome caused by a decrease in blood flow in the coronary arteries. The ACS is usually related to coronary thrombosis and is primarily caused by plaque rupture followed by plaque erosion and calcified nodule. Thin-cap fibroatheroma (TCFA) is known to be the most similar lesion morphologically to a plaque rupture. In
arxiv +1 more source
Advanced Materials, EarlyView.Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li +3 more
wiley +1 more source
Survival intravascular photoacoustic imaging of lipid‐rich plaque in cholesterol fed rabbits
Translational Biophotonics, Volume 4, Issue 4, December 2022., 2022 Early identification of vulnerable plaques in vivo can have a positive impact on guiding the treatment of cardiovascular disease. In this work, Ji‐Xin Cheng and coworkers demonstrate survival intravascular photoacoustic imaging of lipid‐laden plaques in live cholesterol‐fed rabbits.
Yi Zhang +4 more
wiley +1 more source
Wall Shear Stress Analysis in Stenosed Carotid Arteries with Different Shapes of Plaque [PDF]
International Journal of Computer Applications, Volume 145, No.4,
July 2016, 2017 Atherosclerosis is a disease caused due to formation of plaque into the artery. Increase in plaque affects the wall shear stress. The present study is performed to calculate wall shear stress in different geometries of stenosed carotid artery. A 2D model of different geometries is generated using CFD for Non- Newtonian model.
arxiv +1 more source
Two Views on Plaque Rupture [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2007 Plaque rupture probably is the most important cause of myocardial infarction. Plaque rupture is thought to be precipitated by proteases that attack a weakened fibrous cap overlying an inflamed atherosclerotic plaque. Obviously, plaque rupture is of major interest for atherosclerosis researchers and a major target for development of therapy in the ...
Göran K. Hansson, Donald D. Heistad
openaire +2 more sources