Results 71 to 80 of about 755,810 (388)
Improved detection of molecular markers of atherosclerotic plaques using sub-millimeter PET imaging [PDF]
, 2020 Since atherosclerotic plaques are small and sparse, their non-invasive detection via PET imaging requires both highly specific radiotracers as well as imaging systems with high sensitivity and resolution.
Bormans, Guy +11 more
core +2 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Computational Modelling of Atherosclerosis
, 2015 Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk from elevated ...
Baldrick, Francina R +4 more
core +1 more source
, 2014 A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core +1 more source
MRI of Atherothrombosis Associated With Plaque Rupture [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2005 Objective— MRI would be a valuable noninvasive diagnostic tool to study plaque-associated thrombi. We defined the imaging characteristics of these thrombi, composed primarily of platelets and fibrin, and distinguished them clearly from the vessel lumen and underlying atherosclerotic plaque in an ...
Jason Viereck +6 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Indonesian Biomedical Journal, 2009 BACKGROUND: Thrombus is a main cause of cardiac death. Therefore identifying which coronary artery plaque is vulnerable to rupture is a critical step for cardiac intervention to prevent future cardiac events.
Tommy Heryantho +2 more
doaj +1 more source
The role of biomechanics in the assessment of carotid atherosclerosis severity: a numerical approach [PDF]
, 2018 Numerical fluid biomechanics has been proved to be an efficient tool for understanding vascular diseases including atherosclerosis. There are many evidences that atherosclerosis plaque formation and rupture are associated with blood flow ...
Bou-said, Benyebka +4 more
core
Advanced Biology, EarlyView.This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen +4 more
wiley +1 more source
Resolution of Occlusive Carotid Artery Thrombus Treated with Anticoagulation as Demonstrated on Duplex Ultrasonography. [PDF]
, 2017 BACKGROUND AND PURPOSE: While the majority of cerebral ischemic events due to carotid occlusive disease result from atherosclerotic plaque rupture, intraluminal carotid artery thrombus occasionally occurs in patients without preexisting carotid ...
Liang, John W. +2 more
core +2 more sources