Results 111 to 120 of about 2,493,525 (282)
Noah's dove returns: Armenia, Turkey and the debate on genocide / European Stability Initiative
, 2009 Parallel als Buch-Ausg ...
unknown
core +1 more source
Advanced Science, EarlyView.Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan +7 more
wiley +1 more source
Frontiers in Cardiovascular MedicineBackgroundThis systematic review and meta-analysis evaluated the effects of combining probiotics with statins on blood lipids, TMAO, and plaque stability in atherosclerotic patients.MethodsLiterature was systematically searched in PubMed, Cochrane ...
Jie Dong, Lei Chen, Nan Zheng, Ming Yang
doaj +1 more source
TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
Advanced Science, EarlyView.A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Frontiers in Cardiovascular MedicineBackgroundCarotid atherosclerosis (CAS; herein referring to carotid atherosclerotic disease, to be distinguished from carotid artery stenting, which shares the same abbreviation) is a primary driver of ischemic stroke, with inflammation playing a central
Yingwei Li +3 more
doaj +1 more source
Advanced Science, EarlyView.Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He +10 more
wiley +1 more source
Advanced Science, EarlyView.Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang +12 more
wiley +1 more source
Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice
Advanced Science, EarlyView.A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li +12 more
wiley +1 more source
Plaque from Texas Tech University
, 2007 Plaque includes listing of victims from the College of Liberal Arts and Human ...
Texas Tech University
core
Clinical and Translational MedicineBackground Diabetes accelerates atherosclerotic plaque expansion and loss of stability, but the plaque‐resident mechanisms through which the diabetic milieu promotes macrophage lipid‐oxidative injury are not fully understood.
Yanpeng Ma +7 more
doaj +1 more source