Results 91 to 100 of about 78,612 (185)

Research development on gut microbiota and vulnerable atherosclerotic plaque

Heliyon
The relationship between gut microbiota and its metabolites with cardiovascular disease (CVD) has been proven. In this review, we aim to conclude the potential mechanism of gut microbiota and its metabolites on inducing the formation of vulnerable ...
Shujiao Zheng, Zuheng Liu, Haiyue Liu, Jie Ying Lim, Dolly Wong Hui Li, Shaofeng Zhang, Fang Luo, Xiujing Wang, Changqing Sun, Rong Tang, Wuyang Zheng, Qiang Xie   +11 more
doaj   +1 more source

Matrix metalloproteinases at key junctions in the pathomechanism of stroke

, 2011
Matrix metalloproteinases play a crucial role in the remodelling of the extracellular matrix through direct degradation of its structural proteins and control of extracellular signaling.
Kolev, Kraszimir, Kolev Krasimir, Rottenberger Zsolt, Zsolt Rottenberger, Rottenberger, Zsolt, Krasimir Kolev   +5 more
core   +1 more source

Direct association between diet and the stability of human atherosclerotic plaque.

, 2015
Mediterranean diet has been suggested to explain why coronary heart disease mortality is lower in southern than northern Europe. Dietary habits can be revealed by isotope ratio mass spectrometry (IRMS) measurement of carbon (δ(13)C) and nitrogen (δ(15)N)
Stenström, Kristina, Fernandes E Fernandes, José, Nilsson, Jan, Goncalves, Isabel, Pedro, Luís M, Andersson Georgiadou, Elisavet, Georgiadou, Elisavet, Skog, Göran, Engström, Gunnar, Pedro, Luís, Dias, Nuno, Mattsson, Sören   +11 more
core   +1 more source

Characterization of the proteome of stable and unstable carotid atherosclerotic plaques using data-independent acquisition mass spectrometry

Journal of Translational Medicine
Background Currently, noninvasive imaging techniques and circulating biomarkers are still insufficient to accurately assess carotid plaque stability, and an in-depth understanding of the molecular mechanisms that contribute to plaque instability is still
Zhichao Lai, Chaonan Wang, Xiaoyan Liu, Haidan Sun, Zhengguang Guo, Jiang Shao, Kang Li, Junye Chen, Jiaxian Wang, Xiangling Lei, Keqiang Shu, Yuyao Feng, Deqiang Kong, Wei Sun, Bao Liu   +14 more
doaj   +1 more source

The role of smooth muscle cells in plaque stability: Therapeutic targeting potential.

, 2019
Events responsible for cardiovascular mortality and morbidity are predominantly caused by rupture of "vulnerable" atherosclerotic lesions. Vascular smooth muscle cells (VSMCs) play a key role in atherogenesis and have historically been considered ...
Jennifer L. Harman, Helle F. Jørgensen
core   +1 more source

hUC-MSCs mitigate atherosclerosis induced by a high-fat diet in ApoE−/− mice by regulating the intestinal microbiota

Heliyon
Background: The mechanism underlying human umbilical cord mesenchymal stem cells (hUC-MSCs) regulating the stability of atherosclerotic plaque was explored by establishing mice models of atherosclerosis induced by a high-fat diet and hUC-MSCs ...
Lin Yang, Bing Xia, Tianbao Qian, Jie Wang, Yuanhe Wang, Jialin Dai, Cuiyun Le, Xiaorong Yang, Jun Wu, Wenxin Wu, Jianwei Xu, Youbin Liu, Jiawen Wang   +12 more
doaj   +1 more source

DataSheet1_S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.PDF

Introduction: Plaque rupture in atherosclerosis contributes to various acute cardiovascular events. As a new sulfide-containing donor, S-propargyl-cysteine (SPRC) has been reported to play a beneficial role in cardioprotection, potentially through its ...
Zhang Bi-Shan (17836154), Li Ping (427468), Zhu Yi-Chun (17836160), Zhu Lei (17836157), Yu Bo (1509700), Wang Ming-Jie (17836163), Li Zhi-Ming (17836151)   +6 more
core   +1 more source

Coronary artery calcification and plaque stability： an optical coherence tomography study. [PDF]

Heliyon, 2023
Qin Z, Yu L, Zhang Y, Xu Q, Li C, Zhao S, Xi X, Tian Y, Wang Z, Tian J, Yu B.   +10 more
europepmc   +1 more source

Colchicine Promotes Atherosclerotic Plaque Stability via the Notch3-dependent Modulation of Smooth Muscle Cell Phenotype

Atherosclerosis, a chronic inflammatory disease, leads to severe cardiovascular events such as myocardial infarctions and strokes, primarily due to unstable plaque rupture.
Li, Weizhen
core   +1 more source

A Novel Quantitative Mechanical Test of Atherosclerotic Plaque Stability

, 2012
Atherosclerotic plaque rupture is a major cause of myocardial infarction and stroke. The adhesive strength of the bond between the plaque and the vascular wall, measured as local energy release rate, G, was used for quantitative plaque stability ...
Wang, Ying
core