Results 71 to 80 of about 78,612 (185)

Plaque-associated fibroblasts: Key regulators of atherosclerosis pathogenesis and plaque stability [PDF]

Background and objective: Plaque-associated fibroblasts (PAFs) play a crucial role in shaping the plaque’s trajectory, either towards stability or instability. The pathological transformation of fibroblasts into myofibroblasts, characterized by increased
Cau R., Fraschini M., Faa G., Saba L., Castagnola M., Suri J. S.   +5 more
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Sex differences in features of atherosclerotic plaques as revealed by various imaging techniques: historical review

Frontiers in Physiology
Numerous studies over several decades found that there are significant sex differences in the development and severity of atherosclerosis, which include plaque burden, composition and vulnerability to rupture.
Dalya Laban, Alice Kattan, Lamia Ait-Abdellah, Hema Krishna, Hema Krishna, Elizabeth Le Master, Irena Levitan   +6 more
doaj   +1 more source

Carotid plaque vulnerability assessment by microscopic morphology analysis, ultrasound and 3D model reconstruction

, 2012
This thesis was submitted for the degree of Docter of Philosophy and awarded by Brunel University.Research suggests that plaque morphology plays a crucial role in determining plaque vulnerability.
Choudhury, Ahsan
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Matrix metalloproteinases:Influence on smooth muscle cells and atherosclerotic plaque stability

, 2007
Atherosclerotic plaque rupture, with subsequent occlusive thrombosis, is the underlying cause of most cases of sudden cardiac death. Matrix metalloproteinases (MMPs) are thought to mediate the progression of stable atherosclerotic lesions to an unstable ...
Johnson, Jason Lee
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Extracellular matrix in atherosclerotic plaques: its role in plaque stability [PDF]

, 2020
Atherosclerosis is a systemic disease affecting the large arteries caused by the accumulation of lipids in the vessel wall. Cardiovascular disease due to atherosclerosis is today the most common cause of death globally through its end consequences ...
Tengryd, Christoffer
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Carotid Plaque Age Is a Feature of Plaque Stability Inversely Related to Levels of Plasma Insulin

, 2011
C-declination curve (a result of the atomic bomb tests in the 1950s and 1960s) to determine the average biological age of carotid plaques.C content by accelerator mass spectrometry ...
Peter Konrad, Arno Ruusalepp, Ruusalepp Arno, Stefan Rosfors, Konrad Peter, Salehpour Mehran, Sara Hägg, Göran Possnert, Jesper Tegnér, Noori Peri, Possnert Göran, Tegnér Jesper, Jesper Lundström, Takolander Rabbe, Skogsberg Josefin, Peri Noori, Rosfors Stefan, Rabbe Takolander, Lundström Jesper, Björkegren Johan, Johan Björkegren, Josefin Skogsberg, Hägg Sara, Mehran Salehpour   +23 more
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Long non-coding RNA AK023617 orchestrates atherosclerosis by regulating the circadian rhythm of immunity-related GTPase family M protein in macrophages

Non-coding RNA Research
Acute coronary events show a diurnal rhythm, and atherosclerotic plaque vulnerability, as a histomorphological characteristic of major adverse cardiovascular events, is a key target for intervention. Although oscillating microRNAs reduce plaque stability
Rongzhe Lu, Hengxuan Cai, Yige Liu, Guanpeng Ma, Jiaxin Wang, Miao Yan, Zhenming Zhang, Bo Yu, Zhaoying Li, Shaohong Fang   +9 more
doaj   +1 more source

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart [PDF]

, 1996
Plakoglobin (gamma-catenin), a member of the armadillo family of proteins, is a constituent of the cytoplasmic plaque of desmosomes as well as of other adhering cell junctions, and is involved in anchorage of cytoskeletal filaments to specific cadherins.
C Birchmeier, Behrend, M., Günthert, U., B Ledermann, F Vogel, M Behrend, Birchmeier, C., V Brinkmann, P Ruiz, U Günthert, Guenthert, U., Franke, W.W., C Thalhammer, Thalhammer, C., Vogel, F., Birchmeier, W., Ruiz, P., Ledermann, B., C Grund, Franke, W. W., Brinkmann, V., Grund, C., W Birchmeier, W W Franke   +23 more
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Ticagrelor promotes atherosclerotic plaque stability in a mouse model of advanced atherosclerosis

, 2016
Michael R Preusch,1 Jonas Rusnak,1 Kathrin Staudacher,2 Carolin Mogler,3 Lorenz Uhlmann,4 Philipp Sievers,1 Florian Bea,1 Hugo A Katus,1 Erwin Blessing,1 Ingo Staudacher1 1Department of Internal Medicine III, 2Department of Neonatology, 3Department of ...
Rusnak J, Staudacher K, Katus HA, Staudacher I, Preusch MR, Mogler C, Bea F, Blessing E, Uhlmann L, Sievers P   +9 more
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Role of ncRNAs in plaque development, progression, and stability

This chapter provides an overview of the pivotal roles of noncoding RNAs (ncRNAs) in the pathogenesis of atherosclerosis, specifically in plaque development, progression, and stability.
Sachs, Nadja, Mitić, Tijana, Nossent, Anne Yaël, Martelli, Fabio, Greco, Simona   +4 more
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